Targeting and monitoring ovarian cancer invasion with an RNAi and peptide delivery system

L Hao, N Boehnke, SK Elledge… - Proceedings of the …, 2024 - National Acad Sciences
RNA interference (RNAi) therapeutics are an emerging class of medicines that selectively
target mRNA transcripts to silence protein production and combat disease. Despite the …

A dual-signal fluorometric-colorimetric sensing platform and visual detection with a smartphone for the determination of β-galactosidase activity based on fluorescence …

J Liu, Z Li, J Zhang, G Wang, X Su - Talanta, 2022 - Elsevier
As one of primary biomarkers of ovarian cancer in early stages, β-galactosidase (β-Gal) is
significant in the discovery and diagnosis of the disease. In this work, we constructed a multi …

Ultrasensitive surface plasmon resonance sensor with a feature of dynamically tunable sensitivity and high figure of merit for cancer detection

R Gollapalli, J Phillips, P Paul - Sensors, 2023 - mdpi.com
Cancer is one of the leading causes of death worldwide, and it is well known that an early
detection of cancer in a human body will provide an opportunity to cure the cancer. Early …

Emerging technologies in cancer detection

Z Yaari, CP Horoszko, M Antman-Passig, M Kim… - Cancer Biomarkers, 2022 - Elsevier
Exciting, modern technologies for cancer detection are under development in academic and
industrial laboratories worldwide. This chapter provides a synopsis of technologies reaching …

BRET Sensors for Imaging Membrane Integrity of Microfluidically Generated Extracellular Vesicles

R Paulmurugan, Y Liu, UK Sukumar, M Kanada… - … : Methods and Protocols …, 2022 - Springer
Extracellular vesicles (EVs) derived from various cell lines have been extensively used as
natural nanodelivery vehicles for drug, protein, and nucleic acid deliveries in therapeutic …

The need to pair molecular monitoring devices with molecular imaging to personalize health

ZJ Comeau, BH Lessard, AJ Shuhendler - Molecular Imaging and Biology, 2022 - Springer
By enabling the non-invasive monitoring and quantification of biomolecular processes,
molecular imaging has dramatically improved our understanding of disease. In recent years …