[HTML][HTML] Research advances in the detection of miRNA

J Ye, M Xu, X Tian, S Cai, S Zeng - Journal of pharmaceutical analysis, 2019 - Elsevier
MicroRNAs (miRNAs) are a family of endogenous, small (approximately 22 nucleotides in
length), noncoding, functional RNAs. With the development of molecular biology, the …

Rolling circle amplification as an efficient analytical tool for rapid detection of contaminants in aqueous environments

K Zhang, H Zhang, H Cao, Y Jiang, K Mao, Z Yang - Biosensors, 2021 - mdpi.com
Environmental contaminants are a global concern, and an effective strategy for remediation
is to develop a rapid, on-site, and affordable monitoring method. However, this remains …

Label-free homogeneous electrochemical biosensor for HPV DNA based on entropy-driven target recycling and hyperbranched rolling circle amplification

Y He, L Cheng, Y Yang, P Chen, B Qiu, L Guo… - Sensors and Actuators B …, 2020 - Elsevier
Abstract Development of rapid and low-cost detection strategies to screen HPV16 E6 and E7
oncogenes are urgently needed for cervical cancer screening. A highly sensitive, selective …

[HTML][HTML] An aptamer-exonuclease III (Exo III)–assisted amplification-based lateral flow assay for sensitive detection of Escherichia coli O157: H7 in milk

Y Ren, P Gao, Y Song, X Yang, T Yang, S Chen… - Journal of Dairy …, 2021 - Elsevier
ABSTRACT Escherichia coli O157: H7 (E. coli O157: H7), one of the most widespread
foodborne pathogens, can cause a series of diseases and even lead to death. In this study …

Types and applications of nicking enzyme-combined isothermal amplification

S Cao, X Tang, T Chen, G Chen - International Journal of Molecular …, 2022 - mdpi.com
Due to the sudden outbreak of COVID-19 at the end of 2019, rapid detection has become an
urgent need for community clinics and hospitals. The rapid development of isothermal …

Construction of a sensitive protease sensor with DNA-peptide conjugates for single-molecule detection of multiple matrix metalloproteinases

Y Li, W Liu, Q Xu, J Hu, C Zhang - Biosensors and Bioelectronics, 2020 - Elsevier
Protease expression is closely linked to various pathological phenomena, and their accurate
quantification is essential to clinical diagnosis and cancer therapy. Herein, we demonstrate …

Biosensing detection of the SARS-CoV-2 D614G mutation

Y Zhang, H Xi, M Juhas - Trends in Genetics, 2021 - cell.com
The emergence of a mutant strain of severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) with an amino acid change from aspartate to a glycine residue at position …

Simultaneous fluorescent detection of multiplexed miRNA of liver cancer based on DNA tetrahedron nanotags

H Zhao, M Wang, X Xiong, Y Liu, X Chen - Talanta, 2020 - Elsevier
The level of miRNA-21, miRNA-122, and miRNA-223 are always elevated when liver cancer
is present at an early stage. In this paper, a novel assay to simultaneous detect miRNA-21 …

Hairpin DNA-Mediated isothermal amplification (HDMIA) techniques for nucleic acid testing

IA Iwe, W Li, Z Li, J Huang - Talanta, 2021 - Elsevier
Nucleic acid detection is of great importance in a variety of areas, from life science and
clinical diagnosis to environmental monitoring and food safety. Unfortunately, nucleic acid …

Ultrasensitive competitive detection of patulin toxin by using strand displacement amplification and DNA G-quadruplex with aggregation-induced emission

M Zhang, Y Wang, X Sun, J Bai, Y Peng, B Ning… - Analytica Chimica …, 2020 - Elsevier
A novel sensitive assay was established by using strand displacement amplification (SDA)
and DNA G-quadruplex with aggregation-induced emission (AIE) for the detection of patulin …