Cytokines and chemokines in cerebral malaria pathogenesis
Cerebral malaria is among the major causes of malaria-associated mortality and effective
adjunctive therapeutic strategies are currently lacking. Central pathophysiological processes …
adjunctive therapeutic strategies are currently lacking. Central pathophysiological processes …
Cerebral Plasmodium falciparum malaria: The role of PfEMP1 in its pathogenesis and immunity, and PfEMP1‐based vaccines to prevent it
Malaria, a mosquito‐borne infectious disease caused by parasites of the genus Plasmodium
continues to be a major health problem worldwide. The unicellular Plasmodium‐parasites …
continues to be a major health problem worldwide. The unicellular Plasmodium‐parasites …
Malaria-infected erythrocyte-derived microvesicles mediate cellular communication within the parasite population and with the host immune system
PY Mantel, AN Hoang, I Goldowitz, D Potashnikova… - Cell host & …, 2013 - cell.com
Humans and mice infected with different Plasmodium strains are known to produce
microvesicles derived from the infected red blood cells (RBCs), denoted RMVs. Studies in …
microvesicles derived from the infected red blood cells (RBCs), denoted RMVs. Studies in …
The pathogenic basis of malaria
LH Miller, DI Baruch, K Marsh, OK Doumbo - Nature, 2002 - nature.com
Malaria is today a disease of poverty and underdeveloped countries. In Africa, mortality
remains high because there is limited access to treatment in the villages. We should follow …
remains high because there is limited access to treatment in the villages. We should follow …
Infected erythrocyte-derived extracellular vesicles alter vascular function via regulatory Ago2-miRNA complexes in malaria
Malaria remains one of the greatest public health challenges worldwide, particularly in sub-
Saharan Africa. The clinical outcome of individuals infected with Plasmodium falciparum …
Saharan Africa. The clinical outcome of individuals infected with Plasmodium falciparum …
Severe falciparum malaria
World Health Organization - Transactions of the Royal Society of Tropical …, 2000 - Elsevier
A further meeting, sponsored by WHO, was held on 4-8 December 1995 in Geneva. The
purpose was to review in great detail the latest scientific evidence for, and practical …
purpose was to review in great detail the latest scientific evidence for, and practical …
Switches in expression of Plasmodium falciparum var genes correlate with changes in antigenic and cytoadherent phenotypes of infected erythrocytes
Plasmodium falciparum expresses on the host erythrocyte surface clonally variant antigens
and ligands that mediate adherence to endothelial receptors. Both are central to …
and ligands that mediate adherence to endothelial receptors. Both are central to …
The pathogenesis of Plasmodium falciparum malaria in humans: insights from splenic physiology
PA Buffet, I Safeukui, G Deplaine… - Blood, The Journal …, 2011 - ashpublications.org
Clinical manifestations of Plasmodium falciparum infection are induced by the asexual
stages of the parasite that develop inside red blood cells (RBCs). Because splenic …
stages of the parasite that develop inside red blood cells (RBCs). Because splenic …
The role of animal models for research on severe malaria
In light of the recent controversies over the role of animal models for research into the
development of new treatments for severe malaria, particularly cerebral disease, a group of …
development of new treatments for severe malaria, particularly cerebral disease, a group of …
[HTML][HTML] Investigating the pathogenesis of severe malaria: a multidisciplinary and cross-geographical approach
SC Wassmer, TE Taylor, PK Rathod… - The American journal …, 2015 - ncbi.nlm.nih.gov
More than a century after the discovery of Plasmodium spp. parasites, the pathogenesis of
severe malaria is still not well understood. The majority of malaria cases are caused by …
severe malaria is still not well understood. The majority of malaria cases are caused by …