Background: The landscape of attitudes, legal status and patterns of use of cannabis is
rapidly changing in the United States and elsewhere. Therefore, the primary aim of this …

Psychotic disorders (eg, schizophrenia, schizoaffective disorder) are a leading cause of
morbidity and premature mortality and an overlooked health inequity in the United States …

The spread of laws legalising cannabis for medicinal or recreational use has been
accompanied by more relaxed attitudes towards cannabis. Data from the United States show …

Background Psychosis rates are higher among some migrant groups. We hypothesized that
psychosis in migrants is associated with cumulative social disadvantage during different …

Important questions remain about the profile of cognitive impairment in psychotic disorders
across adulthood and illness stages. The age-associated profile of familial impairments also …

BackgroundThe 'jumping to conclusions'(JTC) bias is associated with both psychosis and
general cognition but their relationship is unclear. In this study, we set out to clarify the …

The influence of psychosocial stressors on psychosis risk has usually been studied in
isolation and after the onset of the disorder, potentially ignoring important confounding …

Studies conducted in psychotic disorders have shown that DNA-methylation (DNAm) is
sensitive to the impact of Childhood Adversity (CA). However, whether it mediates the …

Diagnostic categories do not completely reflect the heterogeneous expression of psychosis.
Using data from the EU-GEI study, we evaluated the impact of schizophrenia polygenic risk …

Background A history of childhood adversity is associated with psychotic disorder, with an
increase in risk according to the number of exposures. However, it is not known why only …