The impact of maternal diabetes on the future health and neurodevelopment of the offspring: a review of the evidence

K Rodolaki, V Pergialiotis, N Iakovidou… - Frontiers in …, 2023 - frontiersin.org
Maternal health during gestational period is undoubtedly critical in shaping optimal fetal
development and future health of the offspring. Gestational diabetes mellitus is a metabolic …

Genomic diagnosis of rare pediatric disease in the United Kingdom and Ireland

CF Wright, P Campbell, RY Eberhardt… - … England Journal of …, 2023 - Mass Medical Soc
Background Pediatric disorders include a range of highly penetrant, genetically
heterogeneous conditions amenable to genomewide diagnostic approaches. Finding a …

How do the different types of maternal diabetes during pregnancy influence offspring outcomes?

L Eletri, D Mitanchez - Nutrients, 2022 - mdpi.com
Background/Aim of the study: Exposure to maternal diabetes is considered one of the most
common in utero insults that can result in an increased risk of complications later in life with …

Parental inflammatory bowel disease and autism in children

A Sadik, C Dardani, P Pagoni, A Havdahl… - Nature medicine, 2022 - nature.com
Evidence linking parental inflammatory bowel disease (IBD) with autism in children is
inconclusive. We conducted four complementary studies to investigate associations …

A feature of maternal sleep apnea during gestation causes autism-relevant neuronal and behavioral phenotypes in offspring

AM Vanderplow, BA Kermath, CR Bernhardt… - PLoS …, 2022 - journals.plos.org
Mounting epidemiologic and scientific evidence indicates that many psychiatric disorders
originate from a complex interplay between genetics and early life experiences, particularly …

Childhood neurodevelopmental disorders and maternal diabetes: A population‐based cohort study

KR Chen, T Yu, YJ Lien, YY Chou… - … Medicine & Child …, 2023 - Wiley Online Library
Aim To assess the risk of a wide spectrum of neurodevelopmental disorders (NDDs) in
offspring of mothers with type 1 diabetes mellitus (T1DM), type 2 diabetes mellitus (T2DM) …

Hofbauer cells and fetal brain microglia share transcriptional profiles and responses to maternal diet-induced obesity

R Batorsky, AM Ceasrine, LL Shook, S Kislal, EA Bordt… - Cell Reports, 2024 - cell.com
Maternal immune activation is associated with adverse offspring neurodevelopmental
outcomes, many mediated by in utero microglial programming. As microglia remain …

Rates of maternal weight gain over the course of pregnancy and offspring risk of neurodevelopmental disorders

S Chen, M Fan, BK Lee, C Dalman, H Karlsson… - BMC medicine, 2023 - Springer
Background Previous studies have suggested that gestational weight gain (GWG) outside
an optimal range increases the risks of neurodevelopmental disorders (NDDs) in offspring …

Associations between maternal metabolic conditions and neurodevelopmental conditions in offspring: the mediating effects of obstetric and neonatal complications

S Chen, X Wang, BK Lee, RM Gardner - BMC medicine, 2023 - Springer
Background Maternal pre-gestational diabetes (PGDM), gestational diabetes mellitus
(GDM), and overweight/obesity have been associated with increased risks of offspring …

Could Candida Overgrowth Be Involved in the Pathophysiology of Autism?

A Herman, AP Herman - Journal of Clinical Medicine, 2022 - mdpi.com
The purpose of this review is to summarize the current acquiredknowledge of Candida
overgrowth in the intestine as a possible etiology of autism spectrum disorder (ASD). The …