β-Lactams against the Fortress of the Gram-Positive Staphylococcus aureus Bacterium

JF Fisher, S Mobashery - Chemical reviews, 2020 - ACS Publications
The biological diversity of the unicellular bacteria—whether assessed by shape, food,
metabolism, or ecological niche—surely rivals (if not exceeds) that of the multicellular …

Molecular Determinants of β-Lactam Resistance in Methicillin-Resistant Staphylococcus aureus (MRSA): An Updated Review

H Lade, JS Kim - Antibiotics, 2023 - mdpi.com
The development of antibiotic resistance in Staphylococcus aureus, particularly in methicillin-
resistant S. aureus (MRSA), has become a significant health concern worldwide. The …

In-vitro and in-silico antibacterial activity of Azadirachta indica (Neem), methanolic extract, and identification of Beta.d-Mannofuranoside as a promising antibacterial …

HN Altayb, NF Yassin, S Hosawi, I Kazmi - BMC plant biology, 2022 - Springer
Background Antimicrobial resistance became the leading cause of death globally, resulting
in an urgent need for the discovery of new, safe, and efficient antibacterial agents …

Photocatalytic, dye degradation, and bactericidal behavior of Cu-doped ZnO nanorods and their molecular docking analysis

M Rashid, M Ikram, A Haider, S Naz, J Haider… - Dalton …, 2020 - pubs.rsc.org
Nanostructures of Cu-doped ZnO (Cu: ZnO) were prepared with the chemical precipitation
technique with an aim to enhance the photocatalytic and antibacterial properties of ZnO …

Exploring ligand stability in protein crystal structures using binding pose metadynamics

L Fusani, DS Palmer, DO Somers… - Journal of Chemical …, 2020 - ACS Publications
Identification of correct protein–ligand binding poses is important in structure-based drug
design and crucial for the evaluation of protein–ligand binding affinity. Protein–ligand …

Fluorogenic d-amino acids enable real-time monitoring of peptidoglycan biosynthesis and high-throughput transpeptidation assays

YP Hsu, E Hall, G Booher, B Murphy, AD Radkov… - Nature …, 2019 - nature.com
Peptidoglycan is an essential cell wall component that maintains the morphology and
viability of nearly all bacteria. Its biosynthesis requires periplasmic transpeptidation …

Synergistic antibacterial effects of herbal extracts and antibiotics on methicillin-resistant Staphylococcus aureus: A computational and experimental study

CF Kuok, SO Hoi, CF Hoi, CH Chan… - Experimental …, 2017 - journals.sagepub.com
Antibiotic resistance has become a serious global concern, and the discovery of
antimicrobial herbal constituents may provide valuable solutions to overcome the problem …

Density functional theory and molecular docking investigations of the chemical and antibacterial activities for 1-(4-Hydroxyphenyl)-3-phenylprop-2-en-1-one

AM Deghady, RK Hussein, AG Alhamzani, A Mera - Molecules, 2021 - mdpi.com
The present investigation informs a descriptive study of 1-(4-Hydroxyphenyl)-3-phenylprop-2-
en-1-one compound, by using density functional theory at B3LYP method with 6-311G …

Detection of lipid-linked peptidoglycan precursors by exploiting an unexpected transpeptidase reaction

Y Qiao, MD Lebar, K Schirner, K Schaefer… - Journal of the …, 2014 - ACS Publications
Penicillin-binding proteins (PBPs) are involved in the synthesis and remodeling of bacterial
peptidoglycan (PG). Staphylococcus aureus expresses four PBPs. Genetic studies in S …

[HTML][HTML] PCR-based identification of methicillin–resistant Staphylococcus aureus strains and their antibiotic resistance profiles

A Pournajaf, A Ardebili, L Goudarzi… - Asian pacific journal of …, 2014 - Elsevier
Objective To evaluated the PCR for mecA gene compared with the conventional oxacillin
disk diffusion method for methicillin-resistant Staphylococcus aureus (S. aureus) …