▪ Abstract Neurotransmitter release is mediated by exocytosis of synaptic vesicles at the
presynaptic active zone of nerve terminals. To support rapid and repeated rounds of release …

Rab proteins are best known for their essential roles in exocytic and endocytic membrane
trafficking, which encompass the constitutive and regulated secretory routes, endocytosis via …

Membrane traffic in eukaryotic cells involves transport of vesicles that bud from a donor
compartment and fuse with an acceptor compartment. Common principles of budding and …

In the last years, the classical view of glial cells (in particular of astrocytes) as a simple
supportive cell for neurons has been replaced by a new vision in which glial cells are active …

Rab proteins are small GTPases that play important roles in transport of vesicle cargo and
recruitment, association of motor and other proteins with vesicles, and docking and fusion of …

Alzheimer's disease (AD) is the most common form of dementia worldwide, characterized by
progressive memory impairment, behavioral changes, and, ultimately, loss of consciousness …

Rab3A, Rab3B, Rab3C, and Rab3D are closely related GTP-binding proteins of synaptic
vesicles that may function in neurotransmitter release. We have produced knock-out (KO) …

Skin pigmentation is accomplished by production of melanin in specialized membrane‐
bound organelles termed melanosomes and by transfer of these organelles from …

Rab proteins are small GTPases that act as essential regulators of vesicular trafficking. 44
subfamilies are known in humans, performing specific sets of functions at distinct subcellular …

Synaptic vesicles (SVs) store neurotransmitters and release them by exocytosis. The
vesicular neurotransmitter transporters discriminate which transmitter will be sequestered …