Mixing is a ubiquitous operation in process engineering. It is not only used for combining
materials, but also for promoting heat and mass transfer, increasing aeration, suspending …

Near-infrared spectroscopy (NIRS) is nowadays an established analytical technique in the
pharmaceutical industry. The aim of this review is to present the progress of NIRS in …

Near-infrared (NIR) phosphor-converted light emitting diode (pc-LED) light sources have
broad application prospects in environmental science, biomedical and plant growth fields …

The implementation of process analytical technology and continuous manufacturing at an
FDA approved commercial manufacturing site is described. In this direct compaction process …

Since the completion of the first edition of this book, major developments have occurred in
the pharmaceutical industry that have shaped the field of near-infrared (NIR) spectroscopy …

This study describes the development of a near infrared (NIR) calibration model for real time
determination of drug concentration, powder density, and porosity or relative specific void …

An online near-infrared (NIR) spectroscopy platform system for real-time powder blending
monitoring and blend endpoint determination was tested for a phenytoin sodium formulation …

The application of the Multivariate Curve Resolution by Alternating Least Squares (MCR-
ALS) method to model and control blend processes of pharmaceutical formulations is …

This study focuses on the twin screw granulator of a continuous from-powder-to-tablet
production line. Whereas powder dosing into the granulation unit is possible from a …

In this work, an example of analytical method quality by design (AQbD) principles applied to
an in-line NIR method to monitor blend potency and uniformity in the manufacturing of an …