ENIGMA and global neuroscience: A decade of large-scale studies of the brain in health and disease across more than 40 countries

PM Thompson, N Jahanshad, CRK Ching… - Translational …, 2020 - nature.com
This review summarizes the last decade of work by the ENIGMA (E nhancing N euro I
maging G enetics through M eta A nalysis) Consortium, a global alliance of over 1400 …

Cross disorder comparisons of brain structure in schizophrenia, bipolar disorder, major depressive disorder, and 22q11. 2 deletion syndrome: a review of ENIGMA …

EJ Cheon, CE Bearden, D Sun… - Psychiatry and …, 2022 - Wiley Online Library
This review compares the main brain abnormalities in schizophrenia (SZ), bipolar disorder
(BD), major depressive disorder (MDD), and 22q11. 2 Deletion Syndrome (22q11DS) …

Cortical thickness across the lifespan: Data from 17,075 healthy individuals aged 3–90 years

S Frangou, A Modabbernia, SCR Williams… - Human brain …, 2022 - Wiley Online Library
Delineating the association of age and cortical thickness in healthy individuals is critical
given the association of cortical thickness with cognition and behavior. Previous research …

[HTML][HTML] Cortical brain abnormalities in 4474 individuals with schizophrenia and 5098 control subjects via the enhancing neuro imaging genetics through meta …

TGM Van Erp, E Walton, DP Hibar, L Schmaal… - Biological …, 2018 - Elsevier
Background The profile of cortical neuroanatomical abnormalities in schizophrenia is not
fully understood, despite hundreds of published structural brain imaging studies. This study …

Using deep autoencoders to identify abnormal brain structural patterns in neuropsychiatric disorders: A large‐scale multi‐sample study

WHL Pinaya, A Mechelli, JR Sato - Human brain mapping, 2019 - Wiley Online Library
Abstract Machine learning is becoming an increasingly popular approach for investigating
spatially distributed and subtle neuroanatomical alterations in brain‐based disorders …

Individual-specific functional connectivity markers track dimensional and categorical features of psychotic illness

D Wang, M Li, M Wang, F Schoeppe, J Ren… - Molecular …, 2020 - nature.com
Neuroimaging studies of psychotic disorders have demonstrated abnormalities in structural
and functional connectivity involving widespread brain networks. However, these group …

Derivation and utility of schizophrenia polygenic risk associated multimodal MRI frontotemporal network

S Qi, J Sui, G Pearlson, J Bustillo… - Nature …, 2022 - nature.com
Schizophrenia is a highly heritable psychiatric disorder characterized by widespread
functional and structural brain abnormalities. However, previous association studies …

Cognitive impairment in schizophrenia: relationships with cortical thickness in fronto-temporal regions, and dissociability from symptom severity

E Alkan, G Davies, SL Evans - npj Schizophrenia, 2021 - nature.com
Cognitive impairments are a core and persistent characteristic of schizophrenia with
implications for daily functioning. These show only limited response to antipsychotic …

Multivariate associations among behavioral, clinical, and multimodal imaging phenotypes in patients with psychosis

DA Moser, GE Doucet, WH Lee, A Rasgon… - JAMA …, 2018 - jamanetwork.com
Importance Alterations in multiple neuroimaging phenotypes have been reported in
psychotic disorders. However, neuroimaging measures can be influenced by factors that are …

Cortical and subcortical neuroanatomical signatures of schizotypy in 3004 individuals assessed in a worldwide ENIGMA study

M Kirschner, B Hodzic-Santor, M Antoniades… - Molecular …, 2022 - nature.com
Neuroanatomical abnormalities have been reported along a continuum from at-risk stages,
including high schizotypy, to early and chronic psychosis. However, a comprehensive …