Antioxidant potential overviews of secondary metabolites (polyphenols) in fruits

MS Swallah, H Sun, R Affoh, H Fu… - International journal of …, 2020 - Wiley Online Library
The rise in consumption of energy‐dense foods has resulted in the displacement of several
essential dietary gaps, causing numerous long‐lasting diseases, including obesity, stroke …

[HTML][HTML] The food metabolome: a window over dietary exposure

A Scalbert, L Brennan, C Manach… - The American journal of …, 2014 - Elsevier
The food metabolome is defined as the part of the human metabolome directly derived from
the digestion and biotransformation of foods and their constituents. With> 25,000 …

pH-driven encapsulation of curcumin in self-assembled casein nanoparticles for enhanced dispersibility and bioactivity

K Pan, Y Luo, Y Gan, SJ Baek, Q Zhong - Soft Matter, 2014 - pubs.rsc.org
The poor water solubility and bioactivity of lipophilic phytochemicals can be potentially
improved by delivery systems. In this study, a low-cost, low-energy, and organic solvent-free …

Shifting from the single to the multitarget paradigm in drug discovery

JL Medina-Franco, MA Giulianotti, GS Welmaker… - Drug discovery today, 2013 - Elsevier
Increasing evidence that several drug compounds exert their effects through interactions
with multiple targets is boosting the development of research fields that challenge the data …

Dietary phytochemicals in breast cancer research: anticancer effects and potential utility for effective chemoprevention

A Kapinova, P Kubatka, O Golubnitschaja… - … health and preventive …, 2018 - Springer
Cancerous tissue transformation developing usually over years or even decades of life is a
highly complex process involving strong stressors damaging DNA, chronic inflammation …

The scalable precision medicine open knowledge engine (SPOKE): a massive knowledge graph of biomedical information

JH Morris, K Soman, RE Akbas, X Zhou, B Smith… - …, 2023 - academic.oup.com
Abstract Motivation Knowledge graphs (KGs) are being adopted in industry, commerce and
academia. Biomedical KG presents a challenge due to the complexity, size and …

Dietary phytochemicals in cancer prevention and therapy: a complementary approach with promising perspectives

M González-Vallinas, M González-Castejón… - Nutrition …, 2013 - academic.oup.com
The population is aging. Over the coming years, the incidence of age-related chronic
diseases such as cancer is expected to continue to increase. Phytochemicals, which are non …

Integrative methods for analyzing big data in precision medicine

V Gligorijević, N Malod‐Dognin, N Pržulj - Proteomics, 2016 - Wiley Online Library
We provide an overview of recent developments in big data analyses in the context of
precision medicine and health informatics. With the advance in technologies capturing …

[HTML][HTML] Widely targeted metabolome profiling of different colored sesame (Sesamum indicum L.) seeds provides new insight into their antioxidant activities

SSK Dossou, F Xu, J You, R Zhou, D Li… - Food Research …, 2022 - Elsevier
Sesame seeds are considered worldwide as a functional food due to their nutritional and
therapeutical values. Several physiological functions are being associated with sesame …

MolDiscovery: Learning mass spectrometry fragmentation of small molecules

L Cao, M Guler, A Tagirdzhanov, YY Lee… - Nature …, 2021 - nature.com
Identification of small molecules is a critical task in various areas of life science. Recent
advances in mass spectrometry have enabled the collection of tandem mass spectra of …