Vascular endothelial growth-factor receptors (VEGFRs) regulate the cardiovascular system.
VEGFR1 is required for the recruitment of haematopoietic precursors and migration of …

Endothelial cell migration is essential to angiogenesis. This motile process is directionally
regulated by chemotactic, haptotactic, and mechanotactic stimuli and further involves …

1. From avascular to vascular It is clear that for vasculogenesis and angiogenesis to
effectively proceed during physiological and pathological From the earliest stages, the …

Vascular endothelial growth factors and their endothelial tyrosine kinase receptors are
central regulators of vasculogenesis, angiogenesis and lymphangiogenesis. VEGF …

Angiogenesis is essential for tumor growth, metastasis, arteriosclerosis as well as embryonic
development and wound healing. Its process is dependent on cell proliferation, migration …

Tyrosine phosphorylation is an important signalling mechanism in eukaryotic cells. In
cancer, oncogenic activation of tyrosine kinases is a common feature, and novel anticancer …

Tumour necrosis factor-α (TNFα) is a multifunctional cytokine belonging to a family of ligands
with an associated family of receptor proteins. The pleiotropic actions of TNF range from …

Abbreviations: Apaf, apoptosis protease activation factor; CAD, caspase-activated DNAse;
caspase, cysteine aspartate-directed protease; CAPK, ceramide-activated protein kinase; …

Tissue inhibitors of metalloproteinases (TIMPs) suppress matrix metalloproteinase (MMP)
activity critical for extracellular matrix turnover associated with both physiologic and …

Vascular endothelial growth factors (VEGFs) regulate blood and lymphatic vessel
development and homeostasis but also have profound effects on neural cells. VEGFs are …