Rotavirus entry into a cell is a complex multistep process in which different domains of the
rotavirus surface proteins interact with different cell surface molecules, which act as …

Rotaviruses, the leading cause of severe dehydrating diarrhea in infants and young children
worldwide, are non-enveloped viruses formed by three concentric layers of protein that …

In this work, we have identified the heat shock cognate protein (hsc70) as a receptor
candidate for rotaviruses. hsc70 was shown to be present on the surface of MA104 cells …

Rotavirus infection seems to be a multistep process in which the viruses are required to
interact with several cell surface molecules to enter the cell. The virus spike protein VP4 …

While recently we have learned much about the viral and cellular proteins involved in the
initial attachment of rotaviruses to MA104 cells, the mechanism by which these viruses reach …

In an attempt to identify the rotavirus receptor, we tested 46 cell lines of different species and
tissue origins for susceptibility to infection by three N-acetyl-neuraminic (sialic) acid (SA) …

Rotavirus entry is a complex multistep process that depends on the trypsin cleavage of the
virus spike protein VP4 into polypeptides VP5 and VP8 and on the interaction of these …

Oropharyngeal, airway, intestinal, and genital mucosal epithelia are the main portals of entry
for the majority of human pathogenic viruses. To initiate systemic infection, viruses must first …

Rotavirus cell entry is a multistep process, not completely understood, which requires at
least four interactions between the virus and cell surface molecules. In this work, we …

The picture beginning to form from genome analyses of viruses, unicellular organisms, and
multicellular organisms is that viruses have shared functional modules with cells. A process …