While classical studies on host-parasite interactions have considered a “virulence factor” to
be a molecule (s) that exerts a detrimental effect (that is, toxin) on a host cell, recent …

Discusses the role of bacterial proteinases in matrix destruction and modulation of host
responses. Evasion of host defense mechanisms; Mechanism of gingipain inference with …

In this study the bacterial invasion in root cementum and radicular dentin of periodontally
diseased, caries‐free human teeth was examined. In addition, structural changes in these …

Infections of mucous membranes are mixedinfections (18), with members of the genus
Baicteroidees being the most commonly isolated anaerobes from these sites. In many of …

The classic progression of the development of periodontitis with its associated formation of
an inflammatory lesion is characterized by a highly reproducible microbiological progression …

Collagen is the predominant constituent of skin, tendons, and cartilage as well as the
organic component of bones, teeth, and the cornea. Indeed it constitutes approximately 25 to …

This article discusses about the nature of the periodontal diseases. The major forms of
periodontal disease are now considered to represent bacterial infections in which certain …

A novel arginine-specific cysteine proteinase, termed “argingipain,” was purified from culture
supernatants of Porphyromonas gingivalis, an anaerobe commonly associated with …

Porphyromonas gingivalis, one of the major causative agents of periodontal diseases,
produces large amounts of arginine-and lysine-specific cysteine proteinases in cell …

Discusses the characterization, molecular genetics, effects on host defenses and tissues
and detection in gingival crevice fluid of proteolytic and hydrolytic enzymes from putative …