Current studies of human gut microbiome usually do not consider the special functional role
of transient microbiota, although some of its members remain in the host for a long time and …

Introduction: There is a great interest in Nitric oxide (NO) within medicinal chemistry since it's
involved in human signaling pathways. Prodrugs or hybrid compounds containing NO-donor …

Synthetic strategy for the synthesis of thiophene 2-carboxamide derivatives substituted with
hydroxyl, methyl and amino groups at position-3 was proposed. The strategy includes the …

Nitric oxide (NO) is generated from arginine and oxygen via NO synthase (NOS).
Staphylococcus aureus NOS (saNOS) has previously been shown to affect virulence and …

Herein, we describe a high yielding and switchable synthesis of a range of functionalized
pyridines and pyrroles via Cu-catalyzed cascade reactions with alkynes and N-sulfonyl …

Nitric oxide is produced in Gram-positive pathogens Bacillus anthracis and Staphylococcus
aureus by the bacterial isoform of nitric oxide synthase (NOS). Inhibition of bacterial nitric …

Bacterial infections associated with methicillin-resistant Staphylococcus aureus (MRSA) are
a major economic burden to hospitals, and confer high rates of morbidity and mortality …

Nitric oxide (NO) is a potent inhibitor of diverse cellular processes in bacteria. Therefore, it
was surprising to discover that several bacterial species, primarily Gram-positive organisms …

Nitric oxide synthase (NOS) is a multidomain enzyme that catalyzes the production of nitric
oxide (NO) by oxidizing l‐Arg to NO and L‐citrulline. NO production requires multiple …

The efficacy of quinazoline-based antiglioma agents has been attributed to their effects on
microtubule dynamics. 1, 2 The design, synthesis and biological evaluation of quinazolines …