Spin hyperpolarization in modern magnetic resonance

J Eills, D Budker, S Cavagnero, EY Chekmenev… - Chemical …, 2023 - ACS Publications
Magnetic resonance techniques are successfully utilized in a broad range of scientific
disciplines and in various practical applications, with medical magnetic resonance imaging …

NMR spectroscopy for metabolomics research

AH Emwas, R Roy, RT McKay, L Tenori, E Saccenti… - Metabolites, 2019 - mdpi.com
Over the past two decades, nuclear magnetic resonance (NMR) has emerged as one of the
three principal analytical techniques used in metabolomics (the other two being gas …

Parahydrogen‐based hyperpolarization for biomedicine

JB Hövener, AN Pravdivtsev, B Kidd… - Angewandte Chemie …, 2018 - Wiley Online Library
Magnetic resonance (MR) is one of the most versatile and useful physical effects used for
human imaging, chemical analysis, and the elucidation of molecular structures. However, its …

The theory and practice of hyperpolarization in magnetic resonance using parahydrogen

RA Green, RW Adams, SB Duckett, RE Mewis… - Progress in nuclear …, 2012 - Elsevier
NMR spectroscopy is arguably the most powerful and versatile analytical spectroscopic
method available to analyze nuclides which possess a magnetic dipole moment and …

Signal amplification by reversible exchange (SABRE): From discovery to diagnosis

PJ Rayner, SB Duckett - Angewandte Chemie International …, 2018 - Wiley Online Library
Signal amplification by reversible exchange (SABRE) turns typically weak magnetic
resonance responses into strong signals making previously impractical measurements …

Irreversible catalyst activation enables hyperpolarization and water solubility for NMR signal amplification by reversible exchange

ML Truong, F Shi, P He, B Yuan… - The Journal of …, 2014 - ACS Publications
Activation of a catalyst [IrCl (COD)(IMes)](IMes= 1, 3-bis (2, 4, 6-trimethylphenyl) imidazol-2-
ylidene; COD= cyclooctadiene)] for signal amplification by reversible exchange (SABRE) …

A hyperpolarized equilibrium for magnetic resonance

JB Hövener, N Schwaderlapp, T Lickert… - Nature …, 2013 - nature.com
Nuclear magnetic resonance spectroscopy and imaging (MRI) play an indispensable role in
science and healthcare but use only a tiny fraction of their potential. No more than≈ 10 ppm …

Synergies between hyperpolarized NMR and microfluidics: a review

J Eills, W Hale, M Utz - Progress in Nuclear Magnetic Resonance …, 2022 - Elsevier
Hyperpolarized nuclear magnetic resonance and lab-on-a-chip microfluidics are two
dynamic, but until recently quite distinct, fields of research. Recent developments in both …

Similarity of SABRE field dependence in chemically different substrates

EB Dücker, LT Kuhn, K Münnemann… - Journal of magnetic …, 2012 - Elsevier
The Non-Hydrogenative Parahydrogen-Induced Polarization (NH-PHIP) technique, which is
referred to as Signal Amplification by Reversible Exchange (SABRE), has been reported to …

Heterogeneous solution NMR signal amplification by reversible exchange

F Shi, AM Coffey, KW Waddell… - Angewandte Chemie …, 2014 - Wiley Online Library
A novel variant of an iridium‐based organometallic catalyst was synthesized and used to
enhance the NMR signals of pyridine in a heterogeneous phase by immobilization on …