Glaucoma is a leading cause of irreversible blindness worldwide. Primary open-angle
glaucoma (POAG), the most common type, is a complex inherited disorder that is …

Background Primary open angle glaucoma (POAG) is a chronic, progressive ocular disease
causing loss of the optic nerve rim and retinal nerve fiber layer (RNFL) with associated …

Primary open-angle glaucoma (POAG) is a chronic, progressive optic neuropathy in adults
in which there is a characteristic acquired atrophy of the optic nerve and loss of retinal …

Glaucoma is one of the world's leading causes of irreversible blindness. A complex,
multifactorial disease, the underlying pathogenesis and reasons for disease progression are …

Abstract The Rotterdam Study is a prospective cohort study ongoing since 1990 in the city of
Rotterdam in The Netherlands. The study targets cardiovascular, endocrine, hepatic …

Primary open-angle glaucoma (POAG), the most common optic neuropathy, is a heritable
disease. Siblings of POAG cases have a ten-fold increased risk of developing the disease …

Primary open‐angle glaucoma is the most common optic neuropathy and an important
cause of irreversible blindness worldwide. The optic nerve head or optic disc is divided in …

The search for the genetic determinants of extreme human longevity has been challenged
by the phenotype's rarity and its nonspecific definition by investigators. To address these …

Primary open angle glaucoma (POAG), a major cause of blindness worldwide, is a complex
disease with a significant genetic contribution. We performed Exome Array (Illumina) …

Abstract “Omics” refers to high-throughput analyses of genes, proteins, or metabolites in a
biological system, and is increasingly used for ophthalmic research. These system-based …