Applications and limitations of dendrimers in biomedicine

AA Chis, C Dobrea, C Morgovan, AM Arseniu, LL Rus… - Molecules, 2020 - mdpi.com
Biomedicine represents one of the main study areas for dendrimers, which have proven to
be valuable both in diagnostics and therapy, due to their capacity for improving solubility …

Dendrimers as nanocarriers for nucleic acid and drug delivery in cancer therapy

L Palmerston Mendes, J Pan, VP Torchilin - Molecules, 2017 - mdpi.com
Dendrimers are highly branched polymers with easily modifiable surfaces. This makes them
promising structures for functionalization and also for conjugation with drugs and DNA/RNA …

[HTML][HTML] Emerging innate biological properties of nano-drug delivery systems: A focus on PAMAM dendrimers and their clinical potential

H Kheraldine, O Rachid, AM Habib… - Advanced drug delivery …, 2021 - Elsevier
Drug delivery systems or vectors are usually needed to improve the bioavailability and
effectiveness of a drug through improving its pharmacokinetics/pharmacodynamics at an …

[HTML][HTML] Dendrimers in the context of nanomedicine

AP Dias, S da Silva Santos, JV da Silva… - International journal of …, 2020 - Elsevier
Dendrimers are globular structures, presenting an initiator core, repetitive layers starting
radially from the core and terminal groups on the surface, resembling tree architecture …

A review on drug delivery system for tumor therapy

G Liu, L Yang, G Chen, F Xu, F Yang, H Yu… - Frontiers in …, 2021 - frontiersin.org
In recent years, with the development of nanomaterials, the research of drug delivery
systems has become a new field of cancer therapy. Compared with conventional antitumor …

Applications of dendrimers in nanomedicine and drug delivery: A review

M Nikzamir, Y Hanifehpour, A Akbarzadeh… - Journal of Inorganic and …, 2021 - Springer
Dendrimers are hyper-branched organic compounds characterized via a three-dimensional
structure possessing functional groups on the surface. These terminals groups can be …

Threatening cancer with nanoparticle aided combination oncotherapy

S Rawal, MM Patel - Journal of controlled release, 2019 - Elsevier
Employing combination therapy has become obligatory in cancer cases exhibiting high
tumor load, chemoresistant tumor population, and advanced disease stages. Realization of …

Application of dendrimers in anticancer diagnostics and therapy

Z Bober, D Bartusik-Aebisher, D Aebisher - Molecules, 2022 - mdpi.com
The application of dendrimeric constructs in medical diagnostics and therapeutics is
increasing. Dendrimers have attracted attention due to their compact, spherical three …

The new era of nanotechnology, an alternative to change cancer treatment

A Jurj, C Braicu, LA Pop, C Tomuleasa… - Drug design …, 2017 - Taylor & Francis
In the last few years, nanostructures have gained considerable interest for the safe delivery
of therapeutic agents. Several therapeutic approaches have been reported, such as …

Prospects and challenges of anticancer agents' delivery via chitosan-based drug carriers to combat breast cancer: A review

G Wang, R Li, B Parseh, G Du - Carbohydrate polymers, 2021 - Elsevier
Breast cancer (BC) is considered as one the most prevalent cancers worldwide. Due to its
high resistance to chemotherapy and high probability of metastasis, BC is one of the leading …