A growing subset of metalloenzymes activates dioxygen with nonheme diiron active sites to
effect substrate oxidations that range from the hydroxylation of methane and the …

Redox-active metal ions, Cu (I/II) and Fe (II/III), are essential biological molecules for the
normal functioning of the brain, including oxidative metabolism, synaptic plasticity …

In vivo and in vitro evidence for detoxification of methylmercury (MeHg) as insoluble mercury
selenide (HgSe) underlies the central paradigm that mercury exposure is not or little …

Toxicity of methylmercury (MeHg) to wildlife and humans results from its binding to cysteine
residues of proteins, forming MeHg-cysteinate (MeHgCys) complexes that hinder biological …

Ferritin is the main iron storage protein and plays an important role in maintaining iron
homeostasis. In a previous study, we reported that apoferritin exerted a neuroprotective …

Plant leaves serve both as a sink for gaseous elemental mercury (Hg) from the atmosphere
and a source of toxic mercury to terrestrial ecosystems. Litterfall is the primary deposition …

Ferritins represent a class of iron storage proteins with detoxification functions. The
importance of these proteins is reflected by their wide distribution throughout the animal and …

Parkinson's disease (PD) is a prevalent and advancing age-related neurodegenerative
disorder, distinguished by the degeneration of dopaminergic neurons in the substantia nigra …

Herein, we report on the successful encapsulation into human H-ferritin of two highly
charged Ru (II) polypyridyl complexes,[Ru (phen) 2L′] 2+(Ru1, with L′= 4, 4′-(2, 5, 8, 11 …

Due to its advantageous redox properties, iron plays an important role in the metabolism of
nearly all life. However, these properties are not only a boon but also the bane of such life …