Process intensification offers the potential to drastically reduce the energy consumption and
cost of producing chemicals from both bulk and distributed feedstocks. This review article …

This work presents a review of the main deterministic mixed‐integer nonlinear programming
(MINLP) solution methods for problems with convex and nonconvex functions. An overview …

Filling a void in chemical engineering and optimization literature, this book presents the
theory and methods for nonlinear and mixed-integer optimization, and their applications in …

The first guide to compile current research and frontline developments in the science of
process intensification (PI), Re-Engineering the Chemical Processing Plant illustrates the …

Process alternatives for continuous crystallization, ie, cascades of mixed suspension, mixed
product removal crystallizers (MSMPRCs) and plug flow crystallizers (PFCs), as well as …

In this paper, the synthesis problem of complex nonisothermal reactor networks is
addressed. The focus is on developing a superstructure of alternatives for the nonisothermal …

A geometric framework for studying optimal reactor design is developed. For a given feed
and a prescribed kinetics (perhaps involving many reactions), focus is on the full set of …

In this contribution, a methodology for the optimal design of chemical reactors based on the
best reaction route in the thermodynamic state space is proposed. This route is obtained by …

New chemical products have historically been created by combining a broad knowledge of
existing chemical products with scientific experimentation. Since a combinatorial explosion …

The attainable region approach for reaction–mixing systems is combined with geometric
methods for the feasibility of separations. The result is a systematic approach to identify the …