Fluoropyrimidines such as 5-fluorouracil (5-FU) form the foundation of a wide variety of
chemotherapy regimens. 5-FU is in fact the third most commonly used chemotherapeutic …

Cardio-oncology has organically developed as a new discipline within cardiovascular
medicine as a result of the cardiac and vascular adverse sequelae of the major advances in …

ESC Guidelines e341 (1) the specific situation of the patient. In this respect, it is specified
that, unless otherwise provided for by national regulations, offlabel use of medication should …

Cancer therapy-related cardiac dysfunction (CTRCD) is one of the most feared and
undesirable side effects of chemotherapy, occurring in approximately 10% of the patients. It …

Opinion statement Fluoropyrimidine (FP) is used to treat a wide range of cancers; however, it
is associated with drug-induced vascular toxicity, as well as angina pectoris and coronary …

Colorectal cancer (CRC) is one of the most common forms of cancer, with an estimated 1.36
million new cases and almost 700,000 deaths annually. Approximately 21% of patients with …

Cancer patients experienced an increased risk of cardiotoxicity during fluoropyrimidine-
based chemotherapy (5-fluorouracil or capecitabine). We searched PubMed, PsycINFO, IPA …

Background Capecitabine-or 5-fluorouracil (5-FU)-based chemotherapy is widely used in
many solid tumours, but is associated with cardiotoxicity. S-1 is a fluoropyrimidine with low …

CRC (Colorectal cancer) is one of the most common causes of death worldwide and in the
US (United States). In this study, we aim to perform a population-based analysis on the …

Background: Fluoropyrimidines are mainstay chemotherapeutics in the treatment of
gastrointestinal cancers and are also used to treat breast cancer and head and neck …