Background Cholesteatoma is a gradually expanding destructive epithelial lesion within the
middle ear. It can cause extensive local tissue destruction in the temporal bone and can …

Modeling plays a crucial role in Systems Biology in order to provide a system-level
understanding of biological systems. With the rapid development of systems biology …

Background Quorum sensing drives biofilm formation in bacteria in order to ensure that
biofilm formation only occurs when colonies are of a sufficient size and density. This spatial …

VANESA is a modeling software for the automatic reconstruction and analysis of biological
networks based on life-science database information. Using VANESA, scientists are able to …

Background. Cholesteatoma is a destructive process of the middle ear resulting in erosion of
the surrounding bony structures with consequent hearing loss, vestibular dysfunction, facial …

The CELLmicrocosmos PathwayIntegration (CmPI) was developed to support and visualize
the subcellular localization prediction of protein-related data such as protein-interaction …

During the last 20 years Petri-Nets have attracted more and more attention to help to model
and simulate biological networks. To model the identified features of cellular processing it …

Today, experiments like microarrays and other high-throughput methods generate a large
number of life sciences data. Biologists need to be supported in their research by tools and …

Detailed investigation of socially important diseases with modern experimental methods has
resulted in the generation of large volume of valuable data. However, analysis and …

We present a new Petri net simulation environment to enable the processing of experimental
data to gain usable new insights about biological systems. Therefore, a powerful …