The biological clock system is an intrinsic timekeeping device that integrates internal
physiology and external cues. Maintaining a healthy biological clock system is crucial for life …

Blood pressure (BP) follows a circadian rhythm, it increases on waking in the morning and
decreases during sleeping at night. Disruption of the circadian BP rhythm has been reported …

Background Sleep irregularity has been linked to incident cardiovascular disease. Less is
known about associations of sleep regularity with atherosclerosis. We examined cross …

Simple Summary Metabolic syndrome is a cluster of cardio-metabolic risk factors and
comorbidities, including central obesity, hypertension, hyperglycemia, and dyslipidemia. In …

Circadian clock is a biochemical oscillator in organisms that regulates the circadian rhythm
of numerous genes over 24 h. The circadian clock is involved in telomere homeostasis by …

The circadian rhythm is a self-sustaining 24 h cycle that regulates physiological processes
within the body, including cycles of alertness and sleepiness. Cells have their own intrinsic …

Cleavage and polyadenylation of pre-mRNAs is a necessary step for gene expression and
function. Majority of human genes exhibit multiple polyadenylation sites, which can be …

Although the impacts of macronutrients and the circadian clock on obesity have been
reported, the interactions between macronutrient distribution and circadian genes are …

The growing body of evidence shows a significant difference in the circadian rhythm of
cardiovascular disease based on biological sex. The incidence of cardiovascular disease …

Melatonin is a circadian hormone with antioxidant properties that protects against
myocardial ischemia-reperfusion injury. Genetic variations of the melatonin receptor 1B …