Synapse regulation exploits the capacity of actin to function as a stable structural component
or as a dynamic filament. Beyond its well-appreciated role in eliciting visible morphological …

Neuronal communication crucially relies on exocytosis of neurotransmitters from synaptic
vesicles (SVs) which are clustered at synapses. To ensure reliable neurotransmitter release …

Neurotransmitter-containing synaptic vesicles (SVs) form tight clusters at synapses. These
clusters act as a reservoir from which SVs are drawn for exocytosis during sustained activity …

Energy use, mainly to reverse ion movements in neurons, is a fundamental constraint on
brain information processing. Trafficking of mitochondria to locations in neurons where there …

We present video-rate (28 frames per second) far-field optical imaging with a focal spot size
of 62 nanometers in living cells. Fluorescently labeled synaptic vesicles inside the axons of …

Synaptic vesicle recycling is one of the best‐studied cellular pathways. Many of the proteins
involved are known, and their interactions are becoming increasingly clear. However, as for …

Abstract Information transfer at chemical synapses occurs when vesicles fuse with the
plasma membrane and release neurotransmitter. This process is stochastic and its …

Synaptic vesicles release neurotransmitter at chemical synapses, thus initiating the flow of
information in neural networks. To achieve this, vesicles undergo a dynamic cycle of fusion …

Although the presynaptic protein α-synuclein is a recognized player in neurodegeneration,
its precise physiologic function (s) and/or role in human disease remains unclear. An …

Enlargement of dendritic spines and synapses correlates with enhanced synaptic strength
during long‐term potentiation (LTP), especially in immature hippocampal neurons. Less …