For most complex traits we have a poor understanding of the positions, phenotypic effects,
and population frequencies of the underlying genetic variants contributing to their variation …

It has been hypothesized that individually-rare hidden structural variants (SVs) could
account for a significant fraction of variation in complex traits. Here we identified more than …

Mutations that add, subtract, rearrange, or otherwise refashion genome structure often affect
phenotypes, although the fragmented nature of most contemporary assemblies obscures …

All organisms use resources to grow, survive and reproduce. The supply of these resources
varies widely across landscapes and time, imposing ultimate constraints on the maximal trait …

UDP-glycosyltransferases (UGTs) are important conjugation enzymes found in all kingdoms
of life, catalyzing a sugar conjugation with small lipophilic compounds and playing a crucial …

Using a new experimentally evolved multiparent mapping resource for C. elegans, Noble et
al. have outlined the genetic architecture of worm fertility.. Understanding the genetic basis …

The cotton aphid, Aphis gossypii Glover, is a destructive global crop pest. Control of A.
gossypii has relied heavily on the application of chemical insecticides. The cotton aphid has …

Specialist insect herbivores have evolved efficient ways to adapt to the major defenses of
their host plants. Although Manduca sexta, specialized on Solanaceous plants, has become …

Evolve and resequence studies combine artificial selection experiments with massively
parallel sequencing technology to study the genetic basis for complex traits. In these …

Phenotypic complexity is caused by the contributions of environmental factors and multiple
genetic loci, interacting or acting independently. Studies of yeast and Arabidopsis often find …