The role of negative conductances in neuronal subthreshold properties and synaptic integration

CC Ceballos, AC Roque, RM Leão - Biophysical reviews, 2017 - Springer
Based on passive cable theory, an increase in membrane conductance produces a
decrease in the membrane time constant and input resistance. Unlike the classical leak …

Genetically identified neurons in avian auditory pallium mirror core principles of their mammalian counterparts

JA Spool, M Macedo-Lima, G Scarpa, Y Morohashi… - Current Biology, 2021 - cell.com
In vertebrates, advanced cognitive abilities are typically associated with the telencephalic
pallium. In mammals, the pallium is a layered mixture of excitatory and inhibitory neuronal …

Resurgent Na+ currents promote ultrafast spiking in projection neurons that drive fine motor control

BM Zemel, AA Nevue, A Dagostin, PV Lovell… - Nature …, 2021 - nature.com
The underlying mechanisms that promote precise spiking in upper motor neurons controlling
fine motor skills are not well understood. Here we report that projection neurons in the adult …

Estrogens rapidly shape synaptic and intrinsic properties to regulate the temporal precision of songbird auditory neurons

GB Scarpa, JR Starrett, GL Li, C Brooks… - Cerebral …, 2023 - academic.oup.com
Sensory neurons parse millisecond-variant sound streams like birdsong and speech with
exquisite precision. The auditory pallial cortex of vocal learners like humans and songbirds …

The use of passive cable theory to increase the threshold of nociceptors in people with chronic pain

AA Mohamed, M Alawna - Physical Therapy Reviews, 2021 - Taylor & Francis
Background Chronic pain is one of the disorders that cost any society high expenses. The
major mechanisms responsible for the conversion of pain from acute to chronic are still …

Phasic and tonic cell types in the zebra finch auditory caudal mesopallium

AN Chen, CD Meliza - Journal of neurophysiology, 2018 - journals.physiology.org
The caudal mesopallium (CM) is a cortical-level area in the songbird auditory pathway
where selective, invariant responses to familiar songs emerge. To characterize the cell types …

A negative slope conductance of the persistent sodium current prolongs subthreshold depolarizations

CC Ceballos, AC Roque, RM Leao - Biophysical Journal, 2017 - cell.com
Neuronal subthreshold voltage-dependent currents determine membrane properties such
as the input resistance (R in) and the membrane time constant (τ m) in the subthreshold …

Adult neurogenesis in the songbird: region-specific contributions of new neurons to behavioral plasticity and stability

CL Pytte - Brain Behavior and Evolution, 2016 - karger.com
Our understanding of the role of new neurons in learning and encoding new information has
been largely based on studies of new neurons in the mammalian dentate gyrus and …

Ih Equalizes Membrane Input Resistance in a Heterogeneous Population of Fusiform Neurons in the Dorsal Cochlear Nucleus

CC Ceballos, S Li, AC Roque… - Frontiers in cellular …, 2016 - frontiersin.org
In a neuronal population, several combinations of its ionic conductances are used to attain a
specific firing phenotype. Some neurons present heterogeneity in their firing, generally …

Development of electrophysiological properties of fusiform neurons from the dorsal cochlear nucleus of mice before and after hearing onset

NM Benites, B Rodrigues… - Journal of …, 2023 - journals.physiology.org
The dorsal cochlear nucleus (DCN) in the auditory brainstem integrates auditory and
somatosensory information. Mature DCN fusiform neurons fall into two qualitatively distinct …