Over the past 15 years, there has been great interest in the potential to repurpose the
diabetes drug, metformin, as a cancer treatment. However, despite considerable efforts …

Metformin is a plant-based drug belonging to the class of biguanides and is known to treat
type-2 diabetes mellitus (T2DM). The drug, combined with controlling blood glucose levels …

Human cervical cancer is the fourth most common malignancy among women worldwide,
and it is expected to result in 460,000 deaths per year by 2040. Moreover, patients with …

Metformin is one of the most commonly used first-line oral medications for type 2 diabetes
mellitus. Multiple observational studies, reviewed in numerous systematic reviews, have …

Background To investigate whether metformin monotherapy or adjunctive therapy improves
the prognosis in patients with any type of cancer compared to non-metformin users (age≥ …

Metformin has been the first-line drug for the treatment of type II diabetes mellitus for
decades, being presently the most widely prescribed antihyperglycemic drug. Retrospective …

Metformin and IACS‐010759 are two distinct antimetabolic agents. Metformin, an
established antidiabetic drug, mildly inhibits mitochondrial complex I, while IACS‐010759 is …

Abstract Background and Objective Breast cancer patients treated with adriamycin-
cyclophosphamide plus paclitaxel (AC-T) are often challenged with serious adverse effects …

Breast cancer is one of the most common malignancies in females. It is an etiologically
complex disease driven by a multitude of cellular pathways. The proliferation and spread of …

Breast Cancer (BC) is a carcinoma of breast tissues, the major recurrent cancer in women
and also the foremost cause of death with approximate 5 million annual deaths worldwide …