[HTML][HTML] The remodelling of actin composition as a hallmark of cancer

R Suresh, RJ Diaz - Translational Oncology, 2021 - Elsevier
Actin is a key structural protein that makes up the cytoskeleton of cells, and plays a role in
functions such as division, migration, and vesicle trafficking. It comprises six different cell …

A transcriptome comparison of time-matched developing human, mouse and rat neural progenitor cells reveals human uniqueness

S Masjosthusmann, D Becker, B Petzuch… - Toxicology and applied …, 2018 - Elsevier
It is widely accepted that human brain development has unique features that cannot be
represented by rodents. Obvious reasons are the evolutionary distance and divergent …

E3 Ubiquitin Ligase Uhrf2 Knockout Reveals a Critical Role in Social Behavior and Synaptic Plasticity in the Hippocampus

Y Zhuang, C Li, F Zhao, Y Yan, H Pan, J Zhan… - International Journal of …, 2024 - mdpi.com
The hippocampal formation, particularly the CA2 subregion, is critical for social memory
formation and memory processing, relying on synaptic plasticity—a fundamental mechanism …

Sexually dimorphic transcriptomic changes of developing fetal brain reveal signaling pathways and marker genes of brain cells in domestic pigs

M Strawn, JGN Moraes, TJ Safranski, SK Behura - Cells, 2021 - mdpi.com
In this study, transcriptomic changes of the developing brain of pig fetuses of both sexes
were investigated on gestation days (GD) 45, 60 and 90. Pig fetal brain grows rapidly …

A genomewide association study in divergently selected lines in rabbits reveals novel genomic regions associated with litter size traits

BS Sosa‐Madrid, MA Santacreu… - Journal of Animal …, 2020 - Wiley Online Library
Uterine capacity (UC), defined as the total number of kits from unilaterally ovariectomized
does at birth, has a high genetic correlation with litter size. The aim of our research was to …

Expression of cell type incongruent alpha-cardiac actin 1 subunit in medulloblastoma reveals a novel mechanism for cancer cell survival and control of migration

R Suresh, D Picard, R Lo, J Beaulieu… - Neuro-Oncology …, 2021 - academic.oup.com
Background Alterations in actin subunit expression have been reported in multiple cancers,
but have not been investigated previously in medulloblastoma. Methods Bioinformatic …

[图书][B] Actin subunit structural diversity in Sonic Hedgehog medulloblastoma: implications for cancer biology and neurodevelopment

J Beaulieu - 2022 - search.proquest.com
Actin is one of the most abundant proteins found in cells and has been linked to a wide
range ofcellular functions. Despite having more than a century of documentation on actin …

[PDF][PDF] A genomic region on chromosome 17 has a major impact on litter size traits in rabbits

BS Sosa-Madrid, MA Santacreu… - Proc. World Congr …, 2018 - researchgate.net
Until recently, a genome wide association study in rabbits to identify putative candidate
genes was unfeasible due the lack of high density SNP chips and a reference genome. The …

The role of transcriptomics: physiological equivalence based on gene expression profiles

S Miura, T Himaki, J Takahashi… - Reviews in Agricultural …, 2017 - jstage.jst.go.jp
ABSTRACT DNA microarray and RNA sequencing platforms enable us to simultaneously
measure the expression levels of a large number of genes. These platforms serve as …

[PDF][PDF] 1 0.13 0.13 NRF1 ATP5L TFAP4 HPCA RAB11A AD TOMM 20

NRFTHRAD TOMM - FIU Digital Common s, 2021 - digitalcommons.fiu.edu
6.5. Discussion NRF1 motif-enriched gene signatures of decreased NRF1 transcriptional
activity associated with decreased neurogenesis and increased neurodegenerative …