Circular RNAs: Novel target of diabetic retinopathy

H Zhou, H Kuang - Reviews in Endocrine and Metabolic Disorders, 2021 - Springer
In diabetic patients, diabetic retinopathy (DR) is the leading cause of blindness and
seriously affects the quality of life. However, current treatment methods of DR are not …

Diabetes mellitus associated neurovascular lesions in the retina and brain: A review

SH Sinclair, E Miller, KS Talekar… - Frontiers in …, 2022 - frontiersin.org
Diabetes mellitus (DM) is now recognized as a system-wide, autoimmune, inflammatory,
microvascular disorder, which, in the retina and brain results in severe multifocal injury now …

Gypenoside XVII alleviates early diabetic retinopathy by regulating Müller cell apoptosis and autophagy in db/db mice

Y Luo, X Dong, S Lu, Y Gao, G Sun, X Sun - European Journal of …, 2021 - Elsevier
Diabetic retinopathy (DR) is a widespread vision-threatening disease in working people.
Müller cells are important glial cells that participate in the blood retinal barrier and promote …

[HTML][HTML] Characterizing the retinal phenotype in the high-fat diet and western diet mouse models of prediabetes

B Asare-Bediako, SK Noothi, S Li Calzi… - Cells, 2020 - mdpi.com
We sought to delineate the retinal features associated with the high-fat diet (HFD) mouse, a
widely used model of obesity. C57BL/6 mice were fed either a high-fat (60% fat; HFD) or low …

Retinoprotective effect of wild olive (Acebuche) oil-enriched diet against ocular oxidative stress induced by arterial hypertension

Á Santana-Garrido, C Reyes-Goya, MC Pérez-Camino… - Antioxidants, 2020 - mdpi.com
Oxidative stress plays an important role in the pathogenesis of ocular diseases, including
hypertensive eye diseases. The beneficial effects of olive oil on cardiovascular diseases …

CTSB nuclear translocation facilitates DNA damage and lysosomal stress to promote retinoblastoma cell death

C Li, S Sun, Y Zhuang, Z Luo, G Ji, Z Liu - Molecular Biotechnology, 2024 - Springer
Retinoblastoma (RB) is a pernicious tumor originating from photoreceptor precursor cells
that often endangers the lives of children. The purpose of our study was to further investigate …

[HTML][HTML] Effects of autophagy inhibitor 3-methyladenine on a diabetic mice model

HW Ren, W Yu, YN Wang, XY Zhang… - International Journal …, 2023 - ncbi.nlm.nih.gov
AIM To investigate the role of autophagy inhibitor 3-methyladenine (3-MA) on a diabetic
mice model (DM) and the potential mechanism. METHODS Male C57BL/6J mice were …

Carbamazepine alleviates retinal and optic nerve neural degeneration in diabetic mice via nerve growth factor-induced PI3K/Akt/mTOR activation

NM Elsherbiny, Y Abdel-Mottaleb, AY Elkazaz… - Frontiers in …, 2019 - frontiersin.org
Aim: Diabetic retinopathy causes loss of vision in adults at working-age. Few therapeutic
options are available for treatment of diabetic retinopathy. Carbamazepine (CARB), a widely …

Sestrin2 ameliorates diabetic retinopathy by regulating autophagy and ferroptosis

X Xi, Q Chen, J Ma, X Wang, J Zhang, Y Li - Journal of Molecular Histology, 2024 - Springer
Diabetic retinopathy (DR) is a serious microvascular complication of diabetes. The aim of
this study was to explore the effect of Sestrin2 on DR through the regulation of autophagy …

Metabolomics combined with intestinal microbiota reveals the mechanism of compound Qilian tablets against diabetic retinopathy

J Jia, B Liu, X Wang, F Ji, F Wen, H Xu… - Frontiers in …, 2024 - frontiersin.org
Background Diabetic retinopathy (DR) is one of the common chronic complications of
diabetes mellitus, which has developed into the leading cause of irreversible visual …