Garcinia kola: a critical review on chemistry and pharmacology of an important West African medicinal plant

J Tauchen, A Frankova, A Manourova, I Valterova… - Phytochemistry …, 2023 - Springer
Abstract Garcinia kola Heckel (Clusiaceae) is a tree indigenous to West and Central Africa.
All plant parts, but especially the seeds, are of value in local folklore medicine. Garcinia kola …

Convergent molecular pathways in type 2 diabetes mellitus and parkinson's disease: insights into mechanisms and pathological consequences

S Xxxx, MH Ahmad, L Rani, AC Mondal - Molecular Neurobiology, 2022 - Springer
Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder characterized by
hyperglycemic conditions. A higher risk of developing Parkinson's disease (PD) in patients …

Phytochemical profile, antioxidant, α-amylase inhibition, binding interaction and docking studies of Justicia carnea bioactive compounds with α-amylase

AA Anigboro, OJ Avwioroko, OA Ohwokevwo… - Biophysical …, 2021 - Elsevier
The present study investigated the antioxidant and in vitro antidiabetic capacities of Justicia
carnea aqueous leaf extract (JCAE) using α-amylase inhibition model. α-Amylase binding …

Ginkgo biloba protects striatal neurodegeneration and gut phagoinflammatory damage in rotenone‐induced mice model of Parkinson's disease: Role of executioner …

OG Adebayo, JN Asiwe, B Ben‐Azu… - Journal of Food …, 2022 - Wiley Online Library
Asymptomatic and early clinical stages of Parkinson's disease (PD) have been linked with
comorbid non‐motor symptoms including dysfunction of the gastrointestinal (GI) tract …

Morin ameliorates rotenone-induced Parkinson disease in mice through antioxidation and anti-neuroinflammation: gut-brain axis involvement

IO Ishola, IO Awogbindin, TG Olubodun-Obadun… - Brain Research, 2022 - Elsevier
Parkinson's disease (PD) is the second most common neurodegenerative disorder affecting
both motor and non-motor functions. It is well reported that the neuropathological process …

The Anti-Parkinson Potential of Gingko biloba-Supplement Mitigates Cortico-Cerebellar Degeneration and Neuropathobiological Alterations via Inflammatory and …

OG Adebayo, W Aduema, MU Emmanuel… - Neurochemical …, 2022 - Springer
Activation of nuclear factor erythroid 2 related factor 2 (Nrf2) associated with the suppression
of various oxido-inflammatory pathways and the controller of several gene expressions …

[HTML][HTML] The rotenone models reproducing central and peripheral features of Parkinson's disease

I Miyazaki, M Asanuma - NeuroSci, 2020 - mdpi.com
Parkinson's disease (PD) is a complex, multi-system, neurodegenerative disorder; PD
patients exhibit motor symptoms (such as akinesia/bradykinesia, tremor, rigidity, and …

Roflupram protects against rotenone-induced neurotoxicity and facilitates α-synuclein degradation in Parkinson's disease models

W Dong, J Zhong, Y Chen, J Xie, Y Qin, J Xu… - Acta Pharmacologica …, 2021 - nature.com
We have previously shown that roflupram (ROF) protects against MPP+-induced neuronal
damage in models of Parkinson's disease (PD). Since impaired degradation of α-synuclein …

Omarigliptin attenuates rotenone-induced Parkinson's disease in rats: Possible role of oxidative stress, endoplasmic reticulum stress and immune modulation

HE Michel, MM Tadros, MS Hendy, S Mowaka… - Food and Chemical …, 2022 - Elsevier
The current study aimed to explore the potential neuroprotective effect of omarigliptin (OG),
an antidiabetic drug that crosses the blood-brain barrier (BBB), in a Parkinson's disease …

Kolaviron neuroprotective effect against okadaic acid-provoked cognitive impairment

M Nazari-Serenjeh, T Baluchnejadmojarad… - Heliyon, 2024 - cell.com
Alzheimer's disease (AD) is acknowledged as the main causative factor of dementia that
affects millions of people around the world and is increasing at increasing pace. Okadaic …