Epithelial cell adhesion molecule: an anchor to isolate clinically relevant circulating tumor cells

In the last few decades, the epithelial cell adhesion molecule (EpCAM) has received
increased attention as the main membrane marker used in many enrichment technologies to …

Recent advances in microfluidic cell sorting techniques based on both physical and biochemical principles

W Tang, D Jiang, Z Li, L Zhu, J Shi, J Yang… - …, 2019 - Wiley Online Library
Microfluidic technologies for isolating cells of interest from a heterogeneous sample have
attracted great attentions, due to the advantages of less sample consumption, simple …

Nanomaterial-based immunocapture platforms for the recognition, isolation, and detection of circulating tumor cells

Y Liu, R Li, L Zhang, S Guo - Frontiers in bioengineering and …, 2022 - frontiersin.org
Circulating tumor cells (CTCs) are a type of cancer cells that circulate in the peripheral blood
after breaking away from solid tumors and are essential for the establishment of distant …

Cell separations and sorting

MA Witek, IM Freed, SA Soper - Analytical chemistry, 2019 - ACS Publications
The development of new methods and technologies for cell separation, sorting, selection,
isolation, or enrichment (many times the aforementioned terms are used interchangeably) …

Recent advances in micro-/nanostructure array integrated microfluidic devices for efficient separation of circulating tumor cells

H Kang, Y Xiong, L Ma, T Yang, X Xu - RSC advances, 2022 - pubs.rsc.org
Circulating tumor cells (CTCs) released from the primary tumor to peripheral blood are
promising targets for liquid biopsies. Their biological information is vital for early cancer …

Microfluidic methods for cell separation and subsequent analysis

T Chen, C Huang, Y Wang, J Wu - Chinese Chemical Letters, 2022 - Elsevier
Cell is the most basic unit of the morphological structure and life activity of an organism.
Learning the composition, structure and function of cells, exploring the life activities of cells …

Dual‐isolation and profiling of circulating tumor cells and cancer exosomes from blood samples with melanoma using immunoaffinity‐based microfluidic interfaces

YT Kang, T Hadlock, TW Lo, E Purcell… - Advanced …, 2020 - Wiley Online Library
Melanoma is among the most aggressive cancers, and its rate of incidence continues to
grow. Early detection of melanoma has been hampered due to the lack of promising markers …

On‐chip biogenesis of circulating NK cell‐derived exosomes in non‐small cell lung cancer exhibits antitumoral activity

YT Kang, Z Niu, T Hadlock, E Purcell, TW Lo… - Advanced …, 2021 - Wiley Online Library
As the recognition between natural killer (NK) cells and cancer cells does not require
antigen presentation, NK cells are being actively studied for use in adoptive cell therapies in …

Microfluidic applications on circulating tumor cell isolation and biomimicking of cancer metastasis

X Xu, Z Jiang, J Wang, Y Ren, A Wu - Electrophoresis, 2020 - Wiley Online Library
The prognosis of malignant tumors is challenged by insufficient means to effectively detect
tumors at early stage. Liquid biopsy using circulating tumor cells (CTCs) as biomarkers …

Phenotypic profiling of circulating tumor cells in metastatic prostate cancer patients using nanoparticle-mediated ranking

BJ Green, V Nguyen, E Atenafu, P Weeber… - Analytical …, 2019 - ACS Publications
The analysis of circulating tumor cells (CTCs) provides a means to collect information about
the evolving properties of a tumor during cancer progression and treatment. For patients with …