Intra-articular mesenchymal stem cell injection for knee osteoarthritis: mechanisms and clinical evidence

P Wei, R Bao - International Journal of Molecular Sciences, 2022 - mdpi.com
Knee osteoarthritis presents higher incidences than other joints, with increased prevalence
during aging. It is a progressive process and may eventually lead to disability. Mesenchymal …

A lubricant and adhesive hydrogel cross-linked from hyaluronic acid and chitosan for articular cartilage regeneration

H Qiu, J Deng, R Wei, X Wu, S Chen, Y Yang… - International Journal of …, 2023 - Elsevier
Trauma-induced articular cartilage damages are common in clinical practice. Hydrogels
have been used to fill the cartilage defects and act as extracellular matrices for cell migration …

Osteoarthritis: a common disease that should be avoided in the athletic horse's life

RYA Baccarin, SRT Seidel, YM Michelacci… - Animal …, 2022 - academic.oup.com
Osteoarthritis: a common disease that should be avoided in the athletic horse’s life | Animal
Frontiers | Oxford Academic Skip to Main Content Advertisement Oxford Academic Journals …

Proteoglycan 4 (PRG4)/lubricin and the extracellular matrix in gout

KA Elsaid, GD Jay, R Liu-Bryan… - Gout, Urate, and Crystal …, 2023 - mdpi.com
Proteoglycan 4 (PRG4) is a mucinous glycoprotein secreted by synovial fibroblasts and
superficial zone chondrocytes, released into synovial fluid, and adsorbed on cartilage and …

Zwitterionic Poly‐Carboxybetaine Polymers Restore Lubrication of Inflamed Articular Cartilage

P Weber, M Asadikorayem… - Advanced Healthcare …, 2024 - Wiley Online Library
Osteoarthritis is a degenerative joint disease that is associated with decreased synovial fluid
viscosity and increased cartilage friction. Though viscosupplements are available for …

Scale‐Dependent Rheology of Synovial Fluid Lubricating Macromolecules

L Martin‐Alarcon, A Govedarica, RH Ewoldt, SL Bryant… - Small, 2023 - Wiley Online Library
Synovial fluid (SF) is the complex biofluid that facilitates the exceptional lubrication of
articular cartilage in joints. Its primary lubricating macromolecules, the linear polysaccharide …

Specific Degradation of the Mucin Domain of Lubricin in Synovial Fluid Impairs Cartilage Lubrication

M Prajapati, K Vishwanath, L Huang… - ACS Biomaterials …, 2024 - ACS Publications
Progressive cartilage degradation, synovial inflammation, and joint lubrication dysfunction
are key markers of osteoarthritis. The composition of synovial fluid (SF) is altered in OA, with …

Advances in viscosupplementation and tribosupplementation for early-stage osteoarthritis therapy

CD DeMoya, A Joenathan, TB Lawson… - Nature Reviews …, 2024 - nature.com
Joint kinematic instability, arising from congenital or acquired musculoskeletal
pathoanatomy or from imbalances in anabolism and catabolism induced by …

Equine non‐septic tenosynovitis: A systematic literature review of site‐specific pathological lesions, outcomes and surgical complications

MKK Caspers, CJ Gier… - Equine Veterinary Journal, 2024 - Wiley Online Library
Background Non‐septic tenosynovitis is a clinically relevant and often performance limiting
musculoskeletal injury in the horse. Objectives To review the published literature to …

Optimizing bioink composition for human chondrocyte expression of lubricin

K Martyniak, S Kennedy, M Karimzadeh, MA Cruz… - Bioengineering, 2023 - mdpi.com
The surface zone of articular cartilage is the first area impacted by cartilage defects,
commonly resulting in osteoarthritis. Chondrocytes in the surface zone of articular cartilage …