Importance Epilepsy affects approximately 65 million people worldwide. Persistent seizures
are associated with a 20% to 40% risk of bodily injuries (eg, fractures, burns, concussions) …

Objectives To compare the time to treatment failure, remission and first seizure of 12 AEDs
(carbamazepine, phenytoin, sodium valproate, phenobarbitone, oxcarbazepine, lamotrigine …

В руководстве представлены результаты 60-летней работы автора в области детской
и взрослой неврологии и эпилептологии. Впервые эпилептология представлена в …

Abstract Background Antiseizure drugs (ASDs) are the primary therapy for epilepsy, with
more than 20 drugs introduced into clinical practice to date. These drugs are typically …

The purpose of this report was to update the 2006 International League Against Epilepsy
(ILAE) report and identify the level of evidence for long‐term efficacy or effectiveness for …

More than 150 years after bromide was introduced as the first antiepileptic drug, adverse
effects remain a leading cause of treatment failure and a major determinant of impaired …

Despite the development of various new antiepileptic drugs (AEDs) since the early 1990s,
the available evidence indicates that the efficacy and tolerability of drug treatment of …

Although no randomized studies have demonstrated a positive impact of therapeutic drug
monitoring (TDM) on clinical outcome in epilepsy, evidence from nonrandomized studies …

Epilepsy is a chronic medical disorder or condition, usually resulting in unpredictable,
unprovoked recurrent seizures that affect a variety of mental and physical functions. It is one …

Epilepsy is a serious, potentially life shortening brain disorder, the symptoms of which can
be successfully treated in most patients with one or more antiepileptic drug. About two in …