Ischemic stroke caused by arterial occlusion is the most common type of stroke, which is
among the most frequent causes of disability and death worldwide. Current treatment …

Ferroptosis is a nonapoptotic form of cell death characterized by iron‐dependent
accumulation of lipid hydroperoxides to lethal levels. Necroptosis, an alternative form of …

While many drugs are effective at reducing the relapse frequency of multiple sclerosis (MS),
there is an unmet need for treatments that slow neurodegeneration resulting from secondary …

Rapid increase in aging populations is an urgent problem because older adults are more
likely to suffer from disabilities and age-related diseases (ARDs), burdening healthcare …

Acid-sensing ion channels (ASICs) are mainly proton-gated cation channels that are
activated by pH drops and nonproton ligands. They are part of the degenerin/epithelial …

Glioblastoma is the most aggressive and lethal tumor in the central nervous system in adult
and has poor prognosis due to strong proliferation and aggressive invasion capacity. Acidic …

Acid-sensing ion channels (ASICs) are proton-gated, voltage-independent sodium channels
widely expressed throughout the central and peripheral nervous systems. They are involved …

Background and Purpose. Angong Niuhuang Wan (ANW) is a traditional Chinese herbal
formula that has been widely used for the treatment of ischemic stroke, whereas its …

Acid-sensing ion channel 1a (ASIC1a) is a member of the extracellular H+-activated cation
channel family. Emerging evidence has suggested that ASIC1a plays a crucial role in the …

Age-related diseases have become more common with the advancing age of the worldwide
population. Such diseases involve multiple organs, with tissue degeneration and cellular …