Tumors exhibit areas of decreased oxygenation due to malformed blood vessels. This low
oxygen concentration decreases the effectiveness of radiation therapy, and the resulting …

Restoration of coronary blood flow after a heart attack can cause reperfusion injury
potentially leading to impaired cardiac function, adverse tissue remodeling and heart failure …

Purpose To present a novel registration approach called LATIS (Local Affine Transformation
guided by Internal Structures) for coregistering post prostatectomy pseudo‐whole mount …

Stereotaxy is based on the precise image-guided spatial localization of targets within the
human brain. Even with the recent advances in MRI technology, histological examination …

Background Intracranial neoplasia is relatively common in dogs and stereotactic
radiotherapy, surgical debulking, or both, are the most successful treatment approaches. A …

Three-dimensional brain imaging through cutting-edge MRI technology allows assessment
of physical and chemical tissue properties at sub-millimeter resolution. In order to improve …

Background Magnetic resonance imaging (MRI), together with histology, is widely used to
diagnose and to monitor treatment in oncology. Spatial correspondence between these …

Purpose Magnetic susceptibility (Δχ) alterations have shown association with myocardial
infarction (MI) iron deposition, yet there remains limited understanding of the relationship …

A biomechanical model-based deformable image registration incorporating specimen-
specific changes in material properties is optimized and evaluated for correlating histology …

This work presents two methods that facilitate a 3D reconstruction of microscopic blood
vessels in the volume slightly larger than 1 mm 3. The source of the data are histological …