Deciphering crucial genes in multiple sclerosis pathogenesis and drug repurposing: A systems biology approach

S Dadashkhan, SA Mirmotalebisohi, H Poursheykhi… - Journal of …, 2023 - Elsevier
This study employed systems biology and high-throughput technologies to analyze complex
molecular components of MS pathophysiology, combining data from multiple omics sources …

Investigating the transition of pre-symptomatic to symptomatic huntington's disease status based on omics data

CC Christodoulou, M Zachariou, M Tomazou… - International Journal of …, 2020 - mdpi.com
Huntington's disease is a rare neurodegenerative disease caused by a cytosine–adenine–
guanine (CAG) trinucleotide expansion in the Huntingtin (HTT) gene. Although Huntington's …

PathwayConnector: finding complementary pathways to enhance functional analysis

G Minadakis, M Zachariou, A Oulas, GM Spyrou - Bioinformatics, 2019 - academic.oup.com
PathwayConnector is a web-tool that facilitates the construction of complementary pathway-
to-pathway networks and subnetworks of them, based on a reference pathway network …

[HTML][HTML] PathIN: an integrated tool for the visualization of pathway interaction networks

G Minadakis, K Christodoulou, G Tsouloupas… - Computational and …, 2023 - Elsevier
PathIN is a web-service that provides an easy and flexible way for rapidly creating pathway-
based networks at several functional biological levels: genes, compounds and reactions …

Improved method for analyzing electrical data obtained from EEG for better diagnosis of brain related disorders

AK Dubey, M Saraswat, R Kapoor… - Multimedia Tools and …, 2022 - Springer
Abstract Interpretation of data obtained from electroencephalogram (EEG) has been
commonly used for studying the condition of the brain and to diagnose any abnormalities …

Inhibition of breast cancer cell invasion by Ras suppressor-1 (RSU-1) silencing is reversed by growth differentiation factor-15 (GDF-15)

V Gkretsi, M Louca, A Stylianou, G Minadakis… - International journal of …, 2019 - mdpi.com
Extracellular matrix (ECM)-related adhesion proteins are important in metastasis. Ras
suppressor-1 (RSU-1), a suppressor of Ras-transformation, is localized to cell–ECM …

[PDF][PDF] Diagnosis of Alzheimer disease using machine learning approaches

AR Vidushi, AK Shrivastava - Int. J. Adv. Sci. Technol, 2019 - researchgate.net
This article applies the machine learning paramount techniques for the early detection and
effective diagnosis of severe Alzheimer's disease (AD). AD is neurodegenerative chronic …

[HTML][HTML] Omics and Network-Based Approaches in Understanding HD Pathogenesis

CC Christodoulou, EZ Papanicolaou - 2024 - intechopen.com
Huntington's Disease (HD) is a rare, progressive neurodegenerative disease caused by
CAG repeat expansion in the Huntingtin gene. HD is an incurable disease; therefore, there …

[HTML][HTML] ProtExA: a tool for post-processing proteomics data providing differential expression metrics, co-expression networks and functional analytics

G Minadakis, K Sokratous, GM Spyrou - Computational and Structural …, 2020 - Elsevier
ProTExA is a web-tool that provides a post-processing workflow for the analysis of protein
and gene expression datasets. Using network-based bioinformatics approaches, ProTExA …

[Retracted] Data Integration Method Design of Decision Spatial Information System

D Li - Security and Communication Networks, 2022 - Wiley Online Library
With the development of technology, more and more enterprises have begun to use data
integration analysis to make decisions. The decision spatial information system is an …