The extracellular matrix (ECM) is a complex network with multiple functions, including
specific functions during tissue regeneration. Precisely, the properties of the ECM have been …

Abstract Based on Organ Procurement and Transplantation Network data as of December
2019, more than 113 000 patients require an organ transplantation, yet, over the course of …

Tissue loss and end-stage organ failure are serious health problems across the world.
Natural and synthetic polymer scaffold material based artificial organs play an important role …

Introduction: Durable reconstruction of critical size bone defects is still a surgical challenge
despite the availability of numerous autologous and substitute bone options. In this paper …

Traumatic injuries or cancer resection resulting in large volumetric soft tissue loss requires
surgical reconstruction. Vascular composite allotransplantation (VCA) is an emerging …

In the era of growing interest in stem cells, the availability of donors for transplantation has
become a problem. The isolation of embryonic and fetal cells raises ethical controversies …

Idiopathic pulmonary fibrosis (IPF) is a chronic progressive disease with significant gas
exchange impairment owing to exaggerated extracellular matrix (ECM) deposition and …

The larynx is responsible for breathing, producing sound, and protecting the trachea against
food aspiration through the cough reflex. Nowadays, scaffolding surgery has made it easier …

In vitro models for investigating mechanisms underlying repair and regeneration in lung
disease have advanced greatly in the last decades. Of these models, three-dimensional …

Decellularization approaches have been commonly used as alternative techniques to
reconstruct tissues. However, due to the complex tissue compartmentation of the larynx, the …