In situ architecture of Opa1-dependent mitochondrial cristae remodeling
Cristae membrane state plays a central role in regulating mitochondrial function and cellular
metabolism. The protein Optic atrophy 1 (Opa1) is an important crista remodeler that exists …
metabolism. The protein Optic atrophy 1 (Opa1) is an important crista remodeler that exists …
[HTML][HTML] Cognitive dysfunction induced by cranial radiotherapy: mechanisms and therapeutic methods
X Li, Z Ding - Brain Research Bulletin, 2024 - Elsevier
Cranial radiotherapy can damage normal brain tissues, inducing cognitive dysfunction in
patients. Radiotherapy-induced cognitive dysfunction is associated with hippocampal injury …
patients. Radiotherapy-induced cognitive dysfunction is associated with hippocampal injury …
Neuroprotective effects of saxagliptin against radiation-induced cognitive impairment: Insights on Akt/CREB/SIRT1/BDNF signaling pathway
Radiation-induced cognitive impairment has recently fueled scientific interest with an
increasing prevalence of cancer patients requiring whole brain irradiation (WBI) in their …
increasing prevalence of cancer patients requiring whole brain irradiation (WBI) in their …
[PDF][PDF] 非小细胞肺癌脑转移: 靶向治疗时代的放射治疗
李旭昶， 夏杨晨， 刘芳芳， 袁逊， 褚倩 - 肿瘤, 2024 - tumorsci.org
脑转移对非小细胞肺癌(non-small cell lung cancer, NSCLC) 患者的预后带来重大的不良影响.
在靶向治疗时代, 一系列酪氨酸激酶抑制剂(tyrosine kinase inhibitors, TKIs) 为NSCLC …
在靶向治疗时代, 一系列酪氨酸激酶抑制剂(tyrosine kinase inhibitors, TKIs) 为NSCLC …
[HTML][HTML] Synergistic Antitumor Effects of 177Lu-Octreotide Combined with an ALK Inhibitor in a High-Risk Neuroblastoma Xenograft Model
Background/Objectives: Neuroblastoma (NB) is a childhood cancer with heterogeneous
characteristics, posing challenges to effective treatment. NBs express somatostatin receptors …
characteristics, posing challenges to effective treatment. NBs express somatostatin receptors …
Role of intrinsic apoptosis in environmental exposure health outcomes
L Johnson, KA Sarosiek - Trends in Molecular Medicine, 2024 - cell.com
Environmental exposures are linked to diseases of high public health concern, including
cancer, neurodegenerative disorders, and autoimmunity. These diseases are caused by …
cancer, neurodegenerative disorders, and autoimmunity. These diseases are caused by …
Optimizing the Therapeutic Index for Medulloblastoma by Targeting Apoptosis
SJ Yu - 2023 - search.proquest.com
Medulloblastoma (MB) is the most common central nervous system (CNS) malignancy
affecting children, accounting for 20% of all childhood brain tumors. While current …
affecting children, accounting for 20% of all childhood brain tumors. While current …