SARS-CoV-2 infections manifest with a broad spectrum of presentations, ranging from
asymptomatic infections to severe pneumonia and fatal outcomes. This review centers on …

Tissue-resident memory T (T RM) cells positively correlate with cancer survival, but the anti-
tumor mechanisms underlying this relationship are not understood. This review reconciles …

Lung-tissue-resident memory (T RM) CD8+ T cells are critical for heterosubtypic immunity
against influenza virus (IAV) reinfection. How T RM cells surveil the lung, respond to …

Although the last decade has seen tremendous progress in drugs that treat cystic fibrosis
(CF) due to mutations that lead to protein misfolding, there are approximately 8%–10% of …

The nasal mucosa is frequently the initial site of respiratory viral infection, replication, and
transmission. Recent work has started to clarify the independent responses of epithelial …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron breakthrough
infection (BTI) induced better protection than triple vaccination. To address the underlying …

Pneumonia persists as a public health crisis, representing the leading cause of death due to
infection. Whether respiratory tract infections progress to pneumonia and its sequelae such …

SARS-CoV-2 infection and COVID-19 disease vary with respect to viral variant and host
vaccination status. However, how vaccines, emergent variants, and their intersection shift …

Existing SARS-CoV-2 vaccines offer reasonable protection against serious illness; however,
they are less effective in preventing infections caused by Omicron subvariants. 1 …

CD4 tissue-resident memory T (CD4 TRM) cells are crucial adaptive immune components
involved in preventing influenza A virus (IAV) infection. Despite their importance, their …