Sporulation: A response to starvation in the fission yeast Schizosaccharomyces pombe

H Ohtsuka, K Imada, T Shimasaki, H Aiba - MicrobiologyOpen, 2022 - Wiley Online Library
The fission yeast Schizosaccharomyces pombe employs two main strategies to adapt to the
environment and survive when starved for nutrients. The strategies employ sporulation via …

ecl family genes: Factors linking starvation and lifespan extension in Schizosaccharomyces pombe

H Ohtsuka, Y Otsubo, T Shimasaki… - Molecular …, 2023 - Wiley Online Library
In the fission yeast Schizosaccharomyces pombe, the duration of survival in the stationary
phase, termed the chronological lifespan (CLS), is affected by various environmental factors …

The ecl family gene ecl3+ is induced by phosphate starvation and contributes to sexual differentiation in fission yeast

H Ohtsuka, H Sakata, Y Kitazaki, M Tada… - Journal of Cell …, 2023 - journals.biologists.com
In Schizosaccharomyces pombe, ecl family genes are induced by several signals, such as
starvation of various nutrients, including sulfur, amino acids and Mg2+, and environmental …

Factors governing the transcriptome changes and chronological lifespan of fission yeast during phosphate starvation

A Garg, AM Sanchez, B Schwer, S Shuman - Journal of Biological …, 2024 - ASBMB
Starvation of Schizosaccharomyces pombe for inorganic phosphate elicits adaptive
transcriptome changes in which mRNAs driving ribosome biogenesis, tRNA biogenesis, and …

Response to leucine in Schizosaccharomyces pombe (fission yeast)

H Ohtsuka, T Shimasaki, H Aiba - FEMS Yeast Research, 2022 - academic.oup.com
Leucine (Leu) is a branched-chain, essential amino acid in animals, including humans.
Fungi, including the fission yeast Schizosaccharomyces pombe, can biosynthesize Leu, but …

Response to sulfur in Schizosaccharomyces pombe

H Ohtsuka, T Shimasaki, H Aiba - FEMS Yeast Research, 2021 - academic.oup.com
Sulfur is an essential component of various biologically important molecules, including
methionine, cysteine and glutathione, and it is also involved in coping with oxidative and …

Low‐Molecular Weight Compounds that Extend the Chronological Lifespan of Yeasts, Saccharomyces cerevisiae, and Schizosaccharomyces pombe

H Ohtsuka, T Shimasaki, H Aiba - Advanced Biology, 2024 - Wiley Online Library
Yeast is an excellent model organism for research for regulating aging and lifespan, and the
studies have made many contributions to date, including identifying various factors and …

Extension of chronological lifespan in Schizosaccharomyces pombe

H Ohtsuka, T Shimasaki, H Aiba - Genes to Cells, 2021 - Wiley Online Library
There are several examples in the nature wherein the mechanism of longevity control of
unicellular organisms is evolutionarily conserved with that of higher multicellular organisms …

Cdc13 (cyclin B) is degraded by autophagy under sulfur depletion in fission yeast

H Ohtsuka, Y Hatta, K Hayashi, T Shimasaki… - Autophagy …, 2022 - Taylor & Francis
Cyclins are degraded by the anaphase-promoting complex/cyclosome (APC/C)-mediated
proteasome in normal mitosis. We showed that Cdc13 (cyclin B) is also degraded by …

Structure-based engineering of Tor complexes reveals that two types of yeast TORC1 produce distinct phenotypes

Y Kamada, C Umeda, Y Mukai… - Journal of Cell …, 2024 - journals.biologists.com
Certain proteins assemble into diverse complex states, each having a distinct and unique
function in the cell. Target of rapamycin (Tor) complex 1 (TORC1) plays a central role in …