This review outlines the accomplishments and potential developments of targeted alpha (α)
particle therapy (TAT). It discusses the therapeutic advantages of the short and highly …

Among all existing radionuclides, only a few are of interest for therapeutic applications and
more specifically for targeted alpha therapy (TAT). From this selection, actinium-225 …

Encouraging results from targeted α-therapy have received significant attention from
academia and industry. However, the limited availability of suitable radionuclides has …

α-Emitting radionuclides have been approved for cancer treatment since 2013, with
increasing degrees of success. Despite this clinical utility, little is known regarding the …

Targeted alpha therapy is an emerging strategy for the treatment of disseminated
cancer.[223Ra] RaCl2 is the only clinically approved alpha particle-emitting drug, and it is …

In the last two decades, various nanomaterials have attracted increasing attention in medical
science owing to their unique physical and chemical characteristics. Incorporating …

Actinium-based therapies could revolutionize cancer medicine but remain tantalizing due to
the difficulties in studying and limited knowledge of Ac chemistry. Current efforts focus on …

The present article highlights the important progress made in the last two decades in the
fields of molecular imaging and radionuclide therapy. Advancements in radiometal-based …

Abstract Human kallikrein peptidase 2 (hK2) is a prostate specific enzyme whose expression
is governed by the androgen receptor (AR). AR is the central oncogenic driver of prostate …

Producing pure substances has been the obsession of scientists for centuries and has
defined chemistry as we know it. Nowadays, most of our economy still relies on the chemist …