Subcellular compartmentalization in the biosynthesis and engineering of plant natural produces

L Yao, X Wu, X Jiang, M Shan, Z Zhang, Y Li… - Biotechnology …, 2023 - Elsevier
Plant natural products (PNPs) are specialized metabolites with diverse bioactivities. They
are extensively used in the pharmaceutical, cosmeceutical and food industries. PNPs are …

Medium-and short-chain dehydrogenase/reductase gene and protein families: the SDR superfamily: functional and structural diversity within a family of metabolic and …

KL Kavanagh, H Jörnvall, B Persson… - Cellular and Molecular …, 2008 - Springer
Short-chain dehydrogenases/reductases (SDRs) constitute a large family of NAD (P)(H)-
dependent oxidoreductases, sharing sequence motifs and displaying similar mechanisms …

Aldehyde toxicity and metabolism: the role of aldehyde dehydrogenases in detoxification, drug resistance and carcinogenesis

A Ahmed Laskar, H Younus - Drug metabolism reviews, 2019 - Taylor & Francis
Aldehydes are carbonyl compounds found ubiquitously in the environment, derived from
both natural and anthropogenic sources. As the aldehydes are reactive species, therefore …

The genome of the polar eukaryotic microalga Coccomyxa subellipsoidea reveals traits of cold adaptation

G Blanc, I Agarkova, J Grimwood, A Kuo… - Genome biology, 2012 - Springer
Background Little is known about the mechanisms of adaptation of life to the extreme
environmental conditions encountered in polar regions. Here we present the genome …

The aldo-keto reductase superfamily and its role in drug metabolism and detoxification

OA Barski, SM Tipparaju, A Bhatnagar - Drug metabolism reviews, 2008 - Taylor & Francis
The aldo-keto reductase (AKR) superfamily comprises enzymes that catalyze redox
transformations involved in biosynthesis, intermediary metabolism, and detoxification …

Rice NON-YELLOW COLORING1 is involved in light-harvesting complex II and grana degradation during leaf senescence

M Kusaba, H Ito, R Morita, S Iida, Y Sato… - The Plant …, 2007 - academic.oup.com
Chlorophyll degradation is an aspect of leaf senescence, which is an active process to
salvage nutrients from old tissues. non-yellow coloring1 (nyc1) is a rice (Oryza sativa) stay …

Short-chain dehydrogenases/reductases (SDR): the 2002 update

U Oppermann, C Filling, M Hult, N Shafqat, X Wu… - Chemico-biological …, 2003 - Elsevier
Short-chain dehydrogenases/reductases (SDR) form a large, functionally heterogeneous
protein family presently with about 3000 primary and about 30 3D structures deposited in …

The SDR (short-chain dehydrogenase/reductase and related enzymes) nomenclature initiative

B Persson, Y Kallberg, JE Bray, E Bruford… - Chemico-biological …, 2009 - Elsevier
Short-chain dehydrogenases/reductases (SDR) constitute one of the largest enzyme
superfamilies with presently over 46,000 members. In phylogenetic comparisons, members …

The enzymes of β-lactam biosynthesis

RB Hamed, JR Gomez-Castellanos, L Henry… - Natural product …, 2013 - pubs.rsc.org
Covering: up to May 2012The β-lactam antibiotics and related β-lactamase inhibitors are
amongst the most important small molecules in clinical use. Most, but not all, β-lactams …

Shared transcriptional signature in Caenorhabditis elegans Dauer larvae and long-lived daf-2 mutants implicates detoxification system in longevity assurance

JJ McElwee, E Schuster, E Blanc, JH Thomas… - Journal of Biological …, 2004 - ASBMB
In the nematode Caenorhabditis elegans, formation of the long-lived dauer larva and adult
aging are both controlled by insulin/insulin-like growth factor-1 signaling. Potentially …