Hsp90 is a highly conserved and abundant chaperone. It participates in essential cellular
activities by supporting the maturation process of its client proteins, many of which are …

Phosphorylation of proteins is reversibly controlled by the kinases and phosphatases in
many posttranslational regulation patterns. Protein phosphatase 5 (PPP5C) is a …

Two out of three diseases of the prostate gland affect aging men worldwide. Benign prostatic
hyperplasia (BPH) is a noncancerous enlargement affecting millions of men. Prostate cancer …

Serine/threonine protein phosphatase 5 (PP5) is ubiquitously expressed in eukaryotic cells;
however, its function in cardiomyocytes is unknown. Under basal conditions, PP5 is …

The function of steroid receptors in the cell depends on the chaperone machinery of Hsp90,
as Hsp90 primes steroid receptors for hormone binding and transcriptional activation …

The serine/threonine protein phosphatase 5 (PP5) regulates multiple cellular signaling
networks. A number of cellular factors, including heat shock protein 90 (Hsp90), promote the …

Abstract Protein phosphatase 5 (PP5) is a serine/threonine protein phosphatase that
regulates many cellular functions including steroid hormone signaling, stress response …

Protein phosphatases are important, for example, as functional antagonists of β-adrenergic
stimulation of the mammalian heart. While β-adrenergic stimulations increase the …

The diverse functional cellular roles played by ribonucleic acids (RNA) have emphasized
the need to develop rapid and accurate methodologies to elucidate the relationship between …

The protein HSF-1 is the controlling transcription factor of the heat-shock response (HSR). Its
binding to the heat-shock elements (HSEs) induces the strong upregulation of conserved …