Recent advances in systems and synthetic biology approaches for developing novel cell-factories in non-conventional yeasts

P Patra, M Das, P Kundu, A Ghosh - Biotechnology Advances, 2021 - Elsevier
Microbial bioproduction of chemicals, proteins, and primary metabolites from cheap carbon
sources is currently an advancing area in industrial research. The model yeast …

Metabolic engineering of Saccharomyces cerevisiae: a key cell factory platform for future biorefineries

KK Hong, J Nielsen - Cellular and Molecular Life Sciences, 2012 - Springer
Metabolic engineering is the enabling science of development of efficient cell factories for
the production of fuels, chemicals, pharmaceuticals, and food ingredients through microbial …

Production of fuels and chemicals from xylose by engineered Saccharomyces cerevisiae: a review and perspective

S Kwak, YS Jin - Microbial cell factories, 2017 - Springer
Efficient xylose utilization is one of the most important pre-requisites for developing an
economic microbial conversion process of terrestrial lignocellulosic biomass into biofuels …

Strain engineering of Saccharomyces cerevisiae for enhanced xylose metabolism

SR Kim, YC Park, YS Jin, JH Seo - Biotechnology advances, 2013 - Elsevier
Efficient and rapid fermentation of all sugars present in cellulosic hydrolysates is essential
for economic conversion of renewable biomass into fuels and chemicals. Xylose is one of …

Cell factory engineering

AM Davy, HF Kildegaard, MR Andersen - Cell systems, 2017 - cell.com
Rational approaches to modifying cells to make molecules of interest are of substantial
economic and scientific interest. Most of these efforts aim at the production of native …

Construction of advanced producers of first-and second-generation ethanol in Saccharomyces cerevisiae and selected species of non-conventional yeasts …

J Ruchala, OO Kurylenko, KV Dmytruk… - Journal of Industrial …, 2020 - academic.oup.com
This review summarizes progress in the construction of efficient yeast ethanol producers
from glucose/sucrose and lignocellulose. Saccharomyces cerevisiae is the major industrial …

Cofactor engineering for advancing chemical biotechnology

Y Wang, KY San, GN Bennett - Current opinion in biotechnology, 2013 - Elsevier
Highlights•Global experimental and modeling studies show effects of cofactors.•Ferredoxin
reactions are energetically efficient routes to reduced products.•Protein engineering of …

New biorefineries and sustainable agriculture: Increased food, biofuels, and ecosystem security

HG Chen, YHP Zhang - Renewable and Sustainable Energy Reviews, 2015 - Elsevier
The sustainability revolution is the defining challenge of our time to meet increasing needs
in the energy− food− water nexus without compromising the ability of next generations. To …

Genome-scale modeling for metabolic engineering

E Simeonidis, ND Price - Journal of Industrial Microbiology and …, 2015 - academic.oup.com
We focus on the application of constraint-based methodologies and, more specifically, flux
balance analysis in the field of metabolic engineering, and enumerate recent developments …

Pentose metabolism and conversion to biofuels and high-value chemicals in yeasts

J Ruchala, AA Sibirny - FEMS Microbiology Reviews, 2021 - academic.oup.com
Pentose sugars are widespread in nature and two of them, D-xylose and L-arabinose
belong to the most abundant sugars being the second and third by abundance sugars in dry …