Inflammatory bowel diseases (IBD) encompass two main entities including ulcerative colitis
and Crohn's disease. Although having a common global pathophysiological mechanism …

The recent advent of sophisticated technologies like sequencing and mass spectroscopy
platforms combined with artificial intelligence-powered analytic tools has initiated a new era …

Background Many studies have investigated how nanoplastics (NPs) exposure mediates
nerve and intestinal toxicity through a dysregulated brain-gut axis interaction, but there are …

Juvenile idiopathic arthritis (JIA) is the most common chronic rheumatic disease in children.
The heterogeneity of the disease can be investigated via single-cell RNA sequencing …

Introduction Crohn's disease (CD) is a complex disease, and assessing activity is
challenging due to pathobiologic process eg ECM remodeling, mucosal damage, and …

Crohn's disease (CD) is an inflammatory bowel disease (IBD) with complex clinical
manifestations such as chronic diarrhea, weight loss and hematochezia. Despite the …

In inflammatory bowel diseases (IBD), the most promising therapies targeting cytokines or
immune cell trafficking demonstrate around 40% efficacy. As IBD is a multifactorial …

Objective In patients with Crohn's disease (CD) on combination therapy (infliximab and
immunosuppressant) and stopping infliximab (cohort from the study of infliximab …

Background Several studies have found that primary sclerosing cholangitis (PSC) and
inflammatory bowel disease (IBD) are closely associated. However, the direction and …

Introduction During the last decades, biologics have revolutionized the treatment of Crohn's
disease and ulcerative colitis. Even though the inflammatory bowel disease (IBD) …