Suppressed Akt/GSK-3β/β-catenin signaling contributes to excessive adipogenesis of fibro-adipogenic progenitors after rotator cuff tears
X Lin, P Wang, W Wang, H Zhou, S Zhu, S Feng… - Cell Death …, 2023 - nature.com
Muscular fatty infiltration is a common and troublesome pathology after rotator cuff tears
(RCT), which mainly derives from fibro-adipogenic progenitors (FAPs). Compared to the …
(RCT), which mainly derives from fibro-adipogenic progenitors (FAPs). Compared to the …
Exercise promotes skeletal muscle growth in adolescents via modulating Mettl3-mediated m6A methylation of MyoD in muscle satellite cells
S Feng, H Zhou, X Lin, S Zhu, H Chen, H Zhou… - Cellular & Molecular …, 2024 - Springer
Exercise exerts positive impacts on skeletal muscle health and homeostasis. Emerging
evidence suggests that m6A methylation is involved in various physiological processes …
evidence suggests that m6A methylation is involved in various physiological processes …
[HTML][HTML] Oestrogen suppresses the adipogenesis of fibro/adipogenic progenitors through reactivating the METTL3–ESR1‐mediated loop in post‐menopausal females
Background Post‐menopausal women experience more severe muscular fatty infiltration,
though the mechanisms remain unclear. The decline in estrogen levels is considered as a …
though the mechanisms remain unclear. The decline in estrogen levels is considered as a …
Metformin mitigates adipogenesis of fibro-adipogenic progenitors after rotator cuff tears via activating mTOR/ULK1-mediated autophagy
H Zhou, X Lin, S Feng, S Zhu, H Zhou… - … of Physiology-Cell …, 2024 - journals.physiology.org
Muscular fatty infiltration is a common issue after rotator cuff tears (RCTs), which impair
shoulder function. Females suffer a higher prevalence and a more severe degree of …
shoulder function. Females suffer a higher prevalence and a more severe degree of …
Distinct clinical characteristics of adolescent idiopathic scoliosis with asymmetrical ESR1 expression in paraspinal muscle progenitor cells
H Xin, W Sui, W Mao, J Yang, X Shao - JOR spine, 2024 - Wiley Online Library
Background Previous studies found decreased ESR1 expression of concave paraspinal
muscle progenitor cells could contribute to the initiation and progression of adolescent …
muscle progenitor cells could contribute to the initiation and progression of adolescent …
[HTML][HTML] PIEZO1 activation enhances myogenesis and mitigates muscle degeneration in rotator cuff tear
T Wang, S Feng, H Zhou, W Mao, R Bai, Y Xia… - Regenerative …, 2025 - Elsevier
Muscle degeneration is a common issue caused by rotator cuff tear (RCT) which significantly
affects prognosis. Muscle stem cells (MuSCs) play a crucial role to prevent muscle …
affects prognosis. Muscle stem cells (MuSCs) play a crucial role to prevent muscle …