Recent progress in solid‐state nanopores

K Lee, KB Park, HJ Kim, JS Yu, H Chae… - Advanced …, 2018 - Wiley Online Library
The solid‐state nanopore has attracted much attention as a next‐generation DNA
sequencing tool or a single‐molecule biosensor platform with its high sensitivity of …

Understanding and modelling the magnitude of the change in current of nanopore sensors

W Tang, JP Fried, RD Tilley, JJ Gooding - Chemical Society Reviews, 2022 - pubs.rsc.org
Nanopores are promising sensing devices that can be used for the detection of analytes at
the single molecule level. It is of importance to understand and model the current response …

[HTML][HTML] Identification of single amino acid differences in uniformly charged homopolymeric peptides with aerolysin nanopore

F Piguet, H Ouldali, M Pastoriza-Gallego… - Nature …, 2018 - nature.com
There are still unmet needs in finding new technologies for biomedical diagnostic and
industrial applications. A technology allowing the analysis of size and sequence of short …

[HTML][HTML] Visualizing single-molecule conformational transition and binding dynamics of intrinsically disordered proteins

W Liu, L Chen, D Yin, Z Yang, J Feng, Q Sun… - Nature …, 2023 - nature.com
Intrinsically disordered proteins (IDPs) play crucial roles in cellular processes and hold
promise as drug targets. However, the dynamic nature of IDPs remains poorly understood …

[HTML][HTML] Nanopore sensing at ultra-low concentrations using single-molecule dielectrophoretic trapping

KJ Freedman, LM Otto, AP Ivanov, A Barik… - Nature …, 2016 - nature.com
Single-molecule techniques are being developed with the exciting prospect of
revolutionizing the healthcare industry by generating vast amounts of genetic and proteomic …

[HTML][HTML] Binding mechanisms of intrinsically disordered proteins: theory, simulation, and experiment

L Mollica, LM Bessa, X Hanoulle, MR Jensen… - Frontiers in molecular …, 2016 - frontiersin.org
In recent years, protein science has been revolutionized by the discovery of intrinsically
disordered proteins (IDPs). In contrast to the classical paradigm that a given protein …

Solid-state and polymer nanopores for protein sensing: A review

N Meyer, I Abrao-Nemeir, JM Janot, J Torrent… - Advances in colloid and …, 2021 - Elsevier
In two decades, the solid state and polymer nanopores became attractive method for the
protein sensing with high specificity and sensitivity. They also allow the characterization of …

Resistive-pulse analysis of nanoparticles

L Luo, SR German, WJ Lan, DA Holden… - Annual Review of …, 2014 - annualreviews.org
The development of nanopore fabrication methods during the past decade has led to the
resurgence of resistive-pulse analysis of nanoparticles. The newly developed resistive-pulse …

The binding mechanisms of intrinsically disordered proteins

J Dogan, S Gianni, P Jemth - Physical Chemistry Chemical Physics, 2014 - pubs.rsc.org
Intrinsically disordered proteins (IDPs) and intrinsically disordered regions (IDRs) of proteins
are very common and instrumental for cellular signaling. Recently, a number of studies have …

Single-molecule studies of intrinsically disordered proteins

M Brucale, B Schuler, B Samorì - Chemical reviews, 2014 - ACS Publications
The last 15 years saw a dramatic increase in the number of published papers exposing
research related to the concept of protein disorder and a concomitant increase in the …