Staphylococcus aureus infections: epidemiology, pathophysiology, clinical manifestations, and management

SYC Tong, JS Davis, E Eichenberger… - Clinical microbiology …, 2015 - Am Soc Microbiol
Staphylococcus aureus is a major human pathogen that causes a wide range of clinical
infections. It is a leading cause of bacteremia and infective endocarditis as well as …

Predictors of mortality in Staphylococcus aureus bacteremia

SJ Van Hal, SO Jensen, VL Vaska… - Clinical microbiology …, 2012 - Am Soc Microbiol
Staphylococcus aureus bacteremia (SAB) is an important infection with an incidence rate
ranging from 20 to 50 cases/100,000 population per year. Between 10% and 30% of these …

Development of a vaccine against Staphylococcus aureus invasive infections: Evidence based on human immunity, genetics and bacterial evasion mechanisms

LS Miller, VG Fowler Jr, SK Shukla… - FEMS microbiology …, 2020 - academic.oup.com
Invasive Staphylococcus aureus infections are a leading cause of morbidity and mortality in
both hospital and community settings, especially with the widespread emergence of virulent …

The role of the Panton-Valentine leucocidin toxin in staphylococcal disease: a systematic review and meta-analysis

LJ Shallcross, E Fragaszy, AM Johnson… - The Lancet infectious …, 2013 - thelancet.com
Background Invasive community-onset staphylococcal disease has emerged worldwide
associated with Panton-Valentine leucocidin (PVL) toxin. Whether PVL is pathogenic or an …

[HTML][HTML] Status of vaccine research and development of vaccines for Staphylococcus aureus

BK Giersing, SS Dastgheyb, K Modjarrad, V Moorthy - Vaccine, 2016 - Elsevier
Staphylococcus aureus is a highly versatile gram positive bacterium that is resident as an
asymptomatic colonizer on the skin and in the nasopharynx of approximately 30% of …

Recommendations for sepsis management in resource-limited settings

MW Dünser, E Festic, A Dondorp, N Kissoon… - Intensive care …, 2012 - Springer
Purpose To provide clinicians practicing in resource-limited settings with a framework to
improve the diagnosis and treatment of pediatric and adult patients with sepsis. Methods …

Future challenges and treatment of Staphylococcus aureus bacteremia with emphasis on MRSA

RV Rasmussen, VG Fowler Jr, R Skov… - Future …, 2011 - Taylor & Francis
Staphylococcus aureus bacteremia (SAB) is an urgent medical problem due to its growing
frequency and its poor associated outcome. As healthcare delivery increasingly involves …

Staphopains modulate Staphylococcus aureus biofilm integrity

JM Mootz, CL Malone, LN Shaw… - Infection and …, 2013 - Am Soc Microbiol
Staphylococcus aureus is a known cause of chronic biofilm infections that can reside on
medical implants or host tissue. Recent studies have demonstrated an important role for …

[HTML][HTML] Comparison of community-onset Staphylococcus argenteus and Staphylococcus aureus sepsis in Thailand: a prospective multicentre observational study

N Chantratita, C Wikraiphat, S Tandhavanant… - Clinical microbiology …, 2016 - Elsevier
Staphylococcus argenteus is a globally distributed cause of human infection, but diagnostic
laboratories misidentify this as Staphylococcus aureus. We determined whether there is …

Colonization, pathogenicity, host susceptibility, and therapeutics for Staphylococcus aureus: what is the clinical relevance?

SYC Tong, LF Chen, VG Fowler - Seminars in immunopathology, 2012 - Springer
Staphylococcus aureus is a human commensal that can also cause a broad spectrum of
clinical disease. Factors associated with clinical disease are myriad and dynamic and …