Natural product-derived phytochemicals as potential agents against coronaviruses: A review

JS Mani, JB Johnson, JC Steel, DA Broszczak… - Virus research, 2020 - Elsevier
Coronaviruses are responsible for a growing economic, social and mortality burden, as the
causative agent of diseases such as severe acute respiratory syndrome (SARS), Middle …

[HTML][HTML] Passive antifouling and active self-disinfecting antiviral surfaces

O Lishchynskyi, Y Shymborska, Y Stetsyshyn… - Chemical Engineering …, 2022 - Elsevier
Viruses pose a serious threat to human health and society in general, as virus infections are
one of the main causes of morbidity and mortality. Till May 2022, over 513 million people …

An in-silico evaluation of different Saikosaponins for their potency against SARS-CoV-2 using NSP15 and fusion spike glycoprotein as targets

SK Sinha, A Shakya, SK Prasad, S Singh… - Journal of …, 2021 - Taylor & Francis
Abstract The Public Health Emergency of International Concern declared the widespread
outbreak of SARS-CoV-2 as a global pandemic emergency, which has resulted in 1,773,086 …

Antiviral activity exerted by natural products against human viruses

M Musarra-Pizzo, R Pennisi, I Ben-Amor, G Mandalari… - Viruses, 2021 - mdpi.com
Viral infections are responsible for several chronic and acute diseases in both humans and
animals. Despite the incredible progress in human medicine, several viral diseases, such as …

Phytochemicals as antiviral agents: recent updates

R Ghildiyal, V Prakash, VK Chaudhary, V Gupta… - Plant-derived bioactives …, 2020 - Springer
The epidemic of viral diseases is a global concern, mandating an urgent need of most
promising antivirals. Some of the viral diseases can be cured by approved antiviral drugs …

[HTML][HTML] Virus-induced p38 MAPK activation facilitates viral infection

Y Cheng, F Sun, L Wang, M Gao, Y Xie, Y Sun, H Liu… - Theranostics, 2020 - ncbi.nlm.nih.gov
Rationale: Many viral infections are known to activate the p38 mitogen-activated protein
kinase (MAPK) signaling pathway. However, the role of p38 activation in viral infection and …

Current therapy for chronic hepatitis C: The role of direct-acting antivirals

G Li, E De Clercq - Antiviral research, 2017 - Elsevier
One of the most exciting developments in antiviral research has been the discovery of the
direct-acting antivirals (DAAs) that effectively cure chronic hepatitis C virus (HCV) infections …

A comprehensive review and perspectives on pharmacology and toxicology of saikosaponins

X Li, X Li, N Huang, R Liu, R Sun - Phytomedicine, 2018 - Elsevier
Abstract Background Radix Bupleuri (RB) has been widely used in Chinese Traditional
Medicine for over 2000 years and is currently marketed in China as Chai-Hu-Shu-Gan …

A systematic review of the active saikosaponins and extracts isolated from Radix Bupleuri and their applications

B Yuan, R Yang, Y Ma, S Zhou, X Zhang… - Pharmaceutical …, 2017 - Taylor & Francis
Abstract Context: Radix Bupleuri has been used in traditional Chinese medicine for over
2000 years with functions of relieving exterior syndrome, clearing heat, regulating liver-qi …

Saikosaponin B2 ameliorates depression-induced microglia activation by inhibiting ferroptosis-mediated neuroinflammation and ER stress

X Wang, S Li, J Yu, W Wang, Z Du, S Gao, Y Ma… - Journal of …, 2023 - Elsevier
Abstracts Ethnopharmacological relevance Saikosaponins B2 (SSB2) is one of the main
active components isolated from Radix Bupleuri (Bupleurum chinense DC.), a herb widely …