Antiretroviral treatment, management challenges and outcomes in perinatally HIV‐infected adolescents

AL Agwu, L Fairlie - African Journal of Reproduction and …, 2013 - journals.lww.com
Three decades into the HIV/AIDS epidemic there is a growing cohort of perinatally HIV-
infected adolescents globally. Their survival into adolescence and beyond represent one of …

Drug resistance in the HIV-1-infected paediatric population worldwide: a systematic review

P Rojas Sánchez, A Holguín - Journal of Antimicrobial …, 2014 - academic.oup.com
Background Drug resistance monitoring of the paediatric HIV-1-infected population is
required to optimize treatment success and preserve future treatment options. Objectives To …

Development of HIV drug resistance and therapeutic failure in children and adolescents in rural Tanzania: an emerging public health concern

L Muri, A Gamell, AJ Ntamatungiro, TR Glass… - Aids, 2017 - journals.lww.com
Objective: To investigate the prevalence and determinants of virologic failure and acquired
drug resistance-associated mutations (DRMs) in HIV-infected children and adolescents in …

Paediatric E uropean N etwork for T reatment of AIDS (PENTA) guidelines for treatment of paediatric HIV‐1 infection 2015: optimizing health in preparation for adult life

A Bamford, A Turkova, H Lyall, C Foster, N Klein… - HIV …, 2018 - Wiley Online Library
The 2015 Paediatric E uropean Network for Treatment of AIDS (PENTA) guidelines provide
practical recommendations on the management of HIV‐1 infection in children in E urope and …

Affordable HIV drug-resistance testing for monitoring of antiretroviral therapy in sub-Saharan Africa

SC Inzaule, P Ondoa, T Peter, PN Mugyenyi… - The Lancet Infectious …, 2016 - thelancet.com
Increased provision of antiretroviral therapy in sub-Saharan Africa has led to a growing
number of patients with therapy failure and acquired drug-resistant HIV, driving the demand …

Predictors of treatment failure in HIV-positive children receiving combination antiretroviral therapy: cohort data from Mozambique and Uganda

P Costenaro, M Penazzato, R Lundin… - Journal of the …, 2015 - academic.oup.com
Background Delays detecting treatment failure and switching to second-line combination
antiretroviral therapy (cART) are often observed in human immunodeficiency virus (HIV) …

HIV-1 treatment failure, drug resistance, and clinical outcomes in perinatally infected children and adolescents failing first-line antiretroviral therapy in Western Kenya

W Nyandiko, S Holland, R Vreeman… - JAIDS Journal of …, 2022 - journals.lww.com
Background: Long-term impact of drug resistance in perinatally infected children and
adolescents living with HIV (CALWH) is poorly understood. We determined drug resistance …

Prevalence and predictors of virological failure in pediatric patients on HAART in sub-Saharan Africa: a systematic review and meta-analysis

N Machila, L Libonda, P Habineza, RM Velu… - Pan African Medical …, 2023 - ajol.info
Antiretroviral treatment failure has emerged as a challenge in the management of pediatric
human immunodeficiency virus (HIV) patients, especially in resource-limited countries …

In-depth analysis of HIV-1 drug resistance mutations in HIV-infected individuals failing first-line regimens in West and Central Africa

CJ Villabona-Arenas, N Vidal, E Guichet, L Serrano… - Aids, 2016 - journals.lww.com
Objective: In resource-limited countries, antiretroviral therapy (ART) has been scaled up, but
individual monitoring is still suboptimal. Here, we studied whether or not ART had an impact …

A comparison of clinical outcomes among people living with HIV of different age groups attending queen Elizabeth central hospital outpatient ART Clinic in Malawi

J Chakakala-Chaziya, N Patson, V Samuel… - Frontiers in …, 2023 - frontiersin.org
Introduction Adherence to Antiretroviral Treatment (ART) in children and adolescents living
with HIV in low-resource settings is not extensively studied in large cohort studies including …