GRP78 is a chaperone with anti-apoptotic function associated with aggressive tumors. This
systematic review aimed to evaluate GRP78 expression in cancer and its relation to …

Most breast cancers express the estrogen receptor (ER) receptor and are negative for the
human epidermal growth factor receptor 2 (HER2) receptor. ER+/HER2− cancers are treated …

The endoplasmic reticulum chaperone BiP (also known as GRP-78 or HSPA5) maintains
protein folding to allow cell proliferation and survival and has been implicated in …

Abstract Background Glioblastomas (GBs) are characterised as one of the most aggressive
primary central nervous system tumours (CNSTs). Single-cell sequencing analysis identified …

This study aimed to explore the role of GRP78‐mediated endoplasmic reticulum stress
(ERS) in the synergistic inhibition of colorectal cancer by epigallocatechin‐3‐gallate (EGCG) …

Amongst all types of cancers, breast cancer is recognized as the most common cancer and a
principal cause of morbidity and mortality in women. Endoplasmic reticulum (ER) stress …

Metastasis remains the leading cause (90%) of cancer-related mortality, especially in
metastatic triple-negative breast cancer (TNBC). Improved understanding of molecular …

Cancer is regarded as one of the world's most serious health issues. Glucose regulated
protein (GRP78) exhibits a vital role in the proliferation, invasion, and metastasis of …

Objective BIK and GRP78 have shown differential expression profiles in breast cancer (BC)
tissue, in addition to its important participation in the pathophysiology of cancer. The …

Breast cancer remains one of the leading causes of cancer-related deaths in women
worldwide. While significant advancements have been made in the treatment of breast …